Arterial Mechanics following Living Kidney Donation

Peixoto, Aldo J.

doi:10.2215/cjn.12280720

Cited by 1 publication

(1 citation statement)

References 12 publications

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“…Overall, the study provided no evidence of prognostically important changes in arterial stiffness at 12 months after kidney donation but did suggest a need for further longer term detailed studies. These are expensive and difficult to perform so that further data on arterial stiffness in kidney donors may be slow to accumulate [ 105 , 106 ].…”

Section: Arterial Stiffnessmentioning

confidence: 99%

Risk for subsequent hypertension and cardiovascular disease after living kidney donation: is it clinically relevant?

Ferro

Townend

2021

Clinical Kidney Journal

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The first successful live donor kidney transplant was performed in 1954. Receiving a kidney transplant from a live kidney donor remains the best option for increasing both life expectancy and quality of life in patients with end-stage kidney disease. However, ever since 1954 there have been multiple questions raised on the ethics of live kidney donation in terms of negative impacts on donor life expectancy. Given the close relationship between reduced kidney function in patients with chronic kidney disease and hypertension, cardiovascular disease, and cardiovascular mortality, information on the impact of kidney donation on these is particularly relevant. In this article we review the existing evidence, focusing on the more recent studies, on the impact of kidney donation on all-cause mortality, cardiovascular mortality, cardiovascular disease, hypertension as well as markers of cardiovascular damage including arterial stiffness and uraemic cardiomyopathy. We also discuss the similarities and differences between the pathological reduction in renal function that occurs in chronic kidney disease with the reduction in renal function that occurs because of a donor nephrectomy. Kidney donors perform an altruistic act that benefits individual patients as well as the wider society. They deserve to have high quality evidence on which to make informed decisions.

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Section: Arterial Stiffnessmentioning

confidence: 99%