Arterial hypertension – Clinical trials update 2021

Ghorani, Hussam Al; Götzinger, Felix; Böhm, Michael; Mahfoud, Felix

doi:10.1016/j.numecd.2021.09.007

Cited by 61 publications

(53 citation statements)

References 50 publications

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“…Elderly individuals often have a high prevalence of chronic diseases, especially empty-nest elders ( 26 ). Hypertension is a widespread and severe global public health issue ( 27 ). In this study, for the participants, the prevalence of hypertension was the highest, up to 64.94%.…”

Section: Discussionmentioning

confidence: 99%

Demand analysis of telenursing among empty-nest elderly individuals with chronic diseases based on the Kano model

Yuan

Tao²,

Yu³

et al. 2022

Front. Public Health

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AimThe increase in empty-nest elderly individuals with chronic diseases poses a major challenge to the provision of public health services in China. Telenursing can effectively relieve the pressure of public health services to a certain extent. This study aims to explore the telenursing needs of empty-nest elderly individuals with chronic diseases based on the Kano model to provide references for improving the quality of telenursing.MethodsParticipants were selected from five rural communities and five urban communities in Yangzhou and Nantong, Jiangsu Province, China. A total of 348 empty-nest elderly individuals with chronic diseases were included. The participants received a sociodemographic characteristics questionnaire, and their telenursing needs were surveyed and analyzed based on the Kano model.ResultsOf the 15 quality attributes evaluated by the participants, 3 telenursing services were categorized as “must-be quality”, 5 were categorized as “one-dimensional quality”, 5 were categorized as “attractive quality”, and 2 were categorized as “indifferent quality”. The proportion of individuals who desired telenursing services ranged from 47.41 to 83.62%, the better values (satisfaction) ranged from 35.29–83.98%, and the worse values (dissatisfaction) ranged from 10.91 to 63.27%. There were no significant differences in any items of telenursing needs for between participants in Yangzhou and Nantong (all P > 0.05), and there were also no significant differences in all items between rural and urban communities (all P > 0.05).ConclusionBased on the Kano model, it was found that empty-nest elderly individuals with chronic diseases had a positive attitude toward telenursing and that they had different levels of need for different telenursing services. These findings provided a theoretical basis for medical decision-makers to formulate medical policies and provided a scientific foundation for nursing managers to improve telenursing services to meet the needs of the empty-nest elderly individuals with chronic diseases.

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Section: Discussionmentioning

confidence: 99%

Demand analysis of telenursing among empty-nest elderly individuals with chronic diseases based on the Kano model

Yuan

Tao²,

Yu³

et al. 2022

Front. Public Health

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“…Hypertension is one of the main factors that increase the risk of cardiovascular diseases, including coronary heart disease, stroke, and atrial fibrillation. The presence of this disease entity contributes most to heart failure [96,97]. In 2017, the AHA/ACC defined hypertension as systolic blood pressure (BP) greater or equal to 130 mmHg, or a diastolic BP of 80 mmHg or greater [98].…”

Section: Hypertension and The Effect Of Lycopenementioning

confidence: 99%

Lycopene in the Prevention of Cardiovascular Diseases

Przybylska

Tokarczyk

2022

IJMS

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Cardiovascular diseases (CVDs) are the leading cause of human mortality worldwide. Oxidative stress and inflammation are pathophysiological processes involved in the development of CVD. That is why bioactive food ingredients, including lycopene, are so important in their prevention, which seems to be a compound increasingly promoted in the diet of people with cardiovascular problems. Lycopene present in tomatoes and tomato products is responsible not only for their red color but also for health-promoting properties. It is characterized by a high antioxidant potential, the highest among carotenoid pigments. Mainly for this reason, epidemiological studies show a number of favorable properties between the consumption of lycopene in the diet and a reduced risk of cardiovascular disease. While there is also some controversy in research into its protective effects on the cardiovascular system, growing evidence supports its beneficial role for the heart, endothelium, blood vessels, and health. The mechanisms of action of lycopene are now being discovered and may explain some of the contradictions observed in the literature. This review aims to present the current knowledge in recent years on the preventive role of lycopene cardiovascular disorders.

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“…A significant characteristic of MS is hypertension, as the most common cardiovascular disease cause. [77][78][79][80] The adverse effects of chemical antihypertensive drugs have led many studies to focus on herbal medications. 81 6-Gingerol has shown a beneficial impact on hypertension (Figure 3).…”

Section: Antihypertensive Effectsmentioning

confidence: 99%

Promising influences of gingerols against metabolic syndrome: A mechanistic review

2022

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Metabolic syndrome is an inflammatory disorder characterized by diabetes, obesity, atherosclerosis, and hypertension. Globally, this disease is increasing, especially in developed countries. Supposedly, herbal treatments for this disease likely have fewer adverse effects than chemical medications. Thus, they can be suitable options among the available chemical treatments. Ginger has been used as a spice and medicinal plant in traditional medicine and cooking. This herbal compound and its derivatives, such as 6‐gingerol, have shown promising effects on various molecular aspects of metabolic syndrome. In this study, we reviewed and discussed the significant impacts of gingerol, a derivative of ginger, on metabolic syndrome through various mechanisms. The benefits of 6‐gingerol include its effects on AMP‐activated protein kinase (AMPK), which prevent diabetes, lipid regulating effect (peroxisome proliferator‐activated receptors, PPARs), as well as its effects on enzymes and proteins preventing hyperlipidemia caused by a high‐fat diet. In addition, 6‐gingerol has anti‐atherosclerosis and anti‐hypertension effects through several molecular mechanisms. The current review will discuss various effects of 6‐gingerol on molecular pathways involved in diabetes, obesity, atherosclerosis, and hypertension as characterizing features of metabolic syndrome and suggests that 6‐gingerol can be a potential treatment agent for metabolic syndrome and shed light on a higher requirement for more pre‐clinical and clinical investigations.

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Arterial hypertension – Clinical trials update 2021

Cited by 61 publications

References 50 publications

Demand analysis of telenursing among empty-nest elderly individuals with chronic diseases based on the Kano model

Demand analysis of telenursing among empty-nest elderly individuals with chronic diseases based on the Kano model

Lycopene in the Prevention of Cardiovascular Diseases

Promising influences of gingerols against metabolic syndrome: A mechanistic review

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