Arterial blood gas levels in high altitude Kashmiri population, India

Sayeed, Sheikh Imran; Handoo, Shazia; Wani, Hilal Ahmad; Walvir, Nazia M; Danish, Qazi; Pampori, Rafiq Ahmad

doi:10.18203/2320-6012.ijrms20151177

Cited by 1 publication

(1 citation statement)

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“…A plausible link exists between decreased serotonin synthesis, which is oxygen dependent (Davis et al, 1973), and increased altitude. The arterial partial pressure of oxygen in humans decreases not only at extreme altitude (Grocott et al, 2009) but also at moderate altitudes (between 1400 and 3350 m) (Crapo et al, 1999; Gahutu et al, 2005; Pereira-Victorio et al, 2014; Sayeed et al, 2017). The contribution of smoking to relative hypoxia may be one reason smoking is often positively correlated with suicide risk.…”

Section: Discussionmentioning

confidence: 99%

Effect of Altitude on Veteran Suicide Rates

Sabic

Kious

Boxer

et al. 2019

High Altitude Medicine & Biology

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Aims: Suicide rates in the general population in the United States are correlated with altitude. To explore factors contributing to suicide among military veterans, we examined the relationship between veteran state-level suicide rates and altitude for 2014, including firearm-related and nonfirearm-related rates. Methods: Pearson's coefficients were calculated for altitude and each outcome. Mixed linear models were used to determine the association between suicide and altitude while adjusting for demographic confounds. Results: State mean altitude was significantly correlated with total veteran suicide rate ( r = 0.678, p < 0.0001), veteran firearm-related suicide rate ( r = 0.578, p < 0.0001), and veteran nonfirearm suicide rate ( r = 0.609, p < 0.0001). In mixed models, altitude was significantly correlated with total veteran suicide rate (β = 0.331, p < 0.05), veteran firearm suicides (β = 0.282, p < 0.05), and veteran nonfirearm suicides (β = 0.393, p < 0.05). Conclusion: This study adds to evidence linking altitude and suicide rates, arguing for additional research into the relationship between altitude and suicide among veterans.

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