Artepillin C: A Review

Unique dynamic mode between Artepillin C and human serum albumin implies the characteristics of Brazilian green propolis representative bioactive component

“…As seen in Table 4, in all reported propolis components, ArtC exhibits the second highest binding constant (9.08 × 10 5 L mol −1 ), only lower than that of CAPE (2.15 × 10 6 L mol −1 ). Most interestingly, as one of the most significant components in Brazilian green propolis 10 , the binding interaction between ArtC and HSA is unique dynamic mode, which is evidently different with other propolis components. Stern-Volmer plot indicated that HSA-ArtC seemed to be the dynamic quenching mechanism, due to the increasing of K sv values with the rising of temperature.…”

“…Artepillin C (ArtC; 3, 5-diprenyl-4-hydroxycinnamic acid) ( Fig. 1) is the significant biologically active phenolic ingredient and a primary assessment criteria for quality control in Brazilian green propolis [10][11][12] . ArtC have been also reported to exhibit a wide variety of pharmacological functions, including superior anti-inflammatory, anti-tumor, antimicrobial and antioxidant activities [13][14][15] and so on.…”

Phosphine-Free Suzuki Cross-Coupling Reaction Using an Efficient and Reusable Pd Catalyst in an Aqueous Medium Under Microwave Irradiation

“…It is important to note that our methodology opens a new possibility for the preparation of allylphenols without using excessive heating and excessive reaction times via the well-known Claisen-rearrangement, and can be used in the synthesis of allylphenols for pharmaceutical industry such as alprenolol, and the Eugenol-Niacin hybrids [21,22] . (Figure 1 (79%), 1f (92%), 1h (84%), 1n (77%), 1p (85%), 1t (80%) and 1v (73%), respectively, almost identical to that when the reactions were performed on a 1 mmol scale.…”

Avaliação das atividades antibacteriana e antiparasitária de análogos prenilados do artepillin C e estudo de suas reações de fragmentação em fase gasosa por espectrometria de massas sequencial

“…Misturas complexas, de origem vegetal, extraídas de colmeias resinosas coletadas por abelhas são chamadas de própolis [69][70][71]. A própolis tem sido utilizada na medicina popular durante muitos anos em diversas regiões do mundo no tratamento de diversas doenças [72].…”

“…"Avaliação da atividade antibacteriana e antiparasitária de análogos prenilados do artepillin C e estudo de suas reações de fragmentação em fase gasosa por ESI-MS/MS" O artepillin C possui uma ampla variedade de atividades biológicas reportadas na literatura, com destaque para as atividades antitumoral [89], anticâncer [90], antioxidante [87], anti-inflamatória [91], antifúngica [71,82] e antimicrobiana [71,92]. Além disso, o artepillin C é descrito na literatura o principal composto bioativo responsável pelo efeito antibacteriano da própolis verde [93,94]…”