Artemisia campestris L.: Ethnomedicinal, phytochemical and pharmacological review

Dib, Ikram; Angenot, Luc; Mihamou, Aatika; Ziyyat, Abderrahim; Tits, Monique

doi:10.1016/j.hermed.2016.10.005

Cited by 41 publications

(40 citation statements)

References 68 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The plant is widely spread in Asia, North America, Europe and North Africa [46]. For this species, several ethnopharmacological uses are reported, such as anti-diabetic, anti-inflammatory, antioxidant, antimicrobial and antipyretic [47,48]. Lavandula, of the Lamiaceae family, is an aromatic genus with about 39 species distributed worldwide, from the Mediterranean region, to tropical Africa and the South-East regions of India [49][50][51].…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition, Antioxidant, Anti-Tyrosinase, Anti-Cholinesterase and Cytotoxic Activities of Essential Oils of Six Algerian Plants

et al. 2020

View full text Add to dashboard Cite

In this study, the essential oils (EOs) of six Algerian plants (Artemisia campestris L., Artemisia herba-alba Asso, Juniperus phoenicea L., Juniperus oxycedrus L., Mentha pulegium L. and Lavandula officinalis Chaix) were obtained by hydrodistillation, and their compositions determined by GC-MS and GC-FID. The antioxidant activity of the EOS was evaluated via 2,2′-diphenyl-1-picrylhydrazyl (DPPH), ferric-reducing/antioxidant power (FRAP) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assays. Moreover, their cytotoxic effect was evaluated—as well as their tyrosinase, acetyl- and butyryl-cholinesterase (AChE and BuChE) inhibitory activities. The chemical analyses detected 44, 45, 51, 53, 26 and 40 compounds in EOs of A. campestris, A. herba-alba, J. phoenicea, J. oxycedrus, M. pulegium and L. officinalis, respectively. A. campestris EO was mainly composed of β-pinene (20.7%), while A. herba-alba EO contained davanone D (49.5%) as the main component. α-Pinene (41.8%) was detected as the major constituent in both J. phoenicea (41.8%) and J. oxycedrus (37.8%) EOs. M. pulegium EO was characterized by pulegone as the most abundant (76.9%) compound, while linalool (35.8%) was detected as a major constituent in L. officinalis EO. The antioxidant power evaluation revealed IC50 values ranging from 2.61 to 91.25 mg/mL for DPPH scavenging activity, while the FRAP values ranged from 0.97–8.17 µmol Trolox equivalents (TX)/g sample. In the ABTS assay, the values ranged from 7.01 to 2.40 µmol TX/g sample. In the presence of 1 mg/mL of the samples, tyrosinase inhibition rates ranged from 11.35% to 39.65%, AChE inhibition rates ranged from 40.57% to 73.60% and BuChE inhibition rates ranged from 6.47% to 72.03%. A significant cytotoxic effect was found for A. herba-alba EO. The obtained results support some of the traditional uses of these species in food preservation and for protection against several diseases.

show abstract

Section: Introductionmentioning

confidence: 99%

Chemical Composition, Antioxidant, Anti-Tyrosinase, Anti-Cholinesterase and Cytotoxic Activities of Essential Oils of Six Algerian Plants

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Artemisia herba‐alba and A . campestris are the main medicinal species commonly used as herbal infusions in folk medicine to treat various diseases . A .…”

Section: Introductionmentioning

confidence: 99%

Essential Oil Variability in Natural Populations of Artemisia campestris (L.) and Artemisia herba‐alba (Asso) and Incidence on Antiacetylcholinesterase and Antioxidant Activities

Younsi

Mehdi

Aissi

et al. 2017

Chemistry & Biodiversity

View full text Add to dashboard Cite

The intraspecific variability of Artemisia herba-alba and A. campestris essential oils and the evaluation of their antioxidant and antiacetylcholinesterase activities were determined. Artemisia herba-alba essential oil was found rich in camphor (19.61%), α-thujone (19.40%), β-thujone (9.44%), chrysanthenone (9.26%), and trans-sabinyl acetate (8.43%). The major compounds of A. campestris essential oil were germacrene D (16.38%), β-pinene (16.33%), and limonene (9.17%). Significant variation in the essential oil composition was observed among populations of each species. The divergence between populations was attributed to the variation of some climatic factors such as altitude, annual rainfall, winter cold stress, summer precipitation, summer drought stress, evapotranspiration, and humidity. Artemisia herba-alba and A. campestris essential oils exhibited promising antioxidant and antiacetylcholinesterase activities. The level of activity varied significantly according to the species and the essential oil. The highest scavenging activity (IC = 0.14 mg/ml) and the uppermost capacity to prevent β-carotene bleaching (IC = 0.10 mg/ml) characterized A. campestris from population 6. A. campestris population 3 possessed the uppermost ability to reduce ferric ions (450.7 μmol Fe /g EO). The population 2 of A. campestris showed the strongest antiacetylcholinesterase activity (IC = 0.02 mg/ml). The variation of these activities between the essential oils was explained by their composition differences.

show abstract

“…One of the inhibition parameters examined in the context of this study was lipid peroxidation. Because there are studies showing that pharmacologically investigated Artemisia campestris L. [17] and Artemisia apiacea [18] have the activity of inhibiting lipid peroxidation. Lipid peroxidation is one of the major sources of free radical-mediated injury that directly damages neuronal membranes and yields a number of secondary products such as 4-hydroxy-2-nonenal and malondialdehyde, responsible for extensive cellular damage [10].…”

Section: Type Of Inhibitionmentioning

confidence: 99%

Phenolic Profile and Cholinesterase, Tyrosinase, Urease and Lipid Peroxidation Inhibition Potentials of Artemisia argyi from Ordu, Turkey

Ayvaz

2019

Celal Bayar Üniversitesi Fen Bilimleri Dergisi

View full text Add to dashboard Cite

The present study was designed to reveal a natural resource that could cure for today's major diseases such as Alzheimer, Parkinson and bacterial infection. Furthermore, oxidative stress resulting from lipid peroxidation is a precursor for many diseases. Therefore, anticholinesterase, antityrosinase, antiurease activities and the inhibition potential on lipid peroxidation of methanolic extract of Artemisia argyi collected from Ordu region were tested. The inhibition ratio of extract at 0.3 mg/mL concentration for asetylcholinesterase and butrylcholinesterase were calculated as 8.45 and 10.68%, respectively. IC50 values for tyrosinase and urease inhibition properties were also found as 0.505 mg/mL and 0.225 mg/mL. The all obtained values were compared with known corresponding inhibitors such as galantamine, kojic acid and thiourea. Besides these, 0.1 mg/mL of the extract prevented lipid peroxidation in the ratio of 7.19%. In the scope of this study, the phenolics of the leaves of A. argyi were also analyzed by using HPLC system and pyrogallol was identified as the major component with the 30.16 mg/kg concentration. On the other hand, benzoic acid was not detected in extract. According to obtained results, A. argyi from Ordu, has the proposed characteristics that it can be a natural resource that can be used in the field of medicine for treatment of various diseases especially Alzheimer and Parkinson, in the cosmetic industry for the elimination of skin problems and in the agricultural field in order to prevent the loss of nitrogenous components.

show abstract

Artemisia campestris L.: Ethnomedicinal, phytochemical and pharmacological review

Cited by 41 publications

References 68 publications

Chemical Composition, Antioxidant, Anti-Tyrosinase, Anti-Cholinesterase and Cytotoxic Activities of Essential Oils of Six Algerian Plants

Chemical Composition, Antioxidant, Anti-Tyrosinase, Anti-Cholinesterase and Cytotoxic Activities of Essential Oils of Six Algerian Plants

Essential Oil Variability in Natural Populations of Artemisia campestris (L.) and Artemisia herba‐alba (Asso) and Incidence on Antiacetylcholinesterase and Antioxidant Activities

Phenolic Profile and Cholinesterase, Tyrosinase, Urease and Lipid Peroxidation Inhibition Potentials of Artemisia argyi from Ordu, Turkey

Contact Info

Product

Resources

About