Artemisia arborescens L essential oil-loaded solid lipid nanoparticles for potential agricultural application: Preparation and characterization

Abstract

The aim of this study was to formulate a new delivery system for ecological pesticides by the incorporation of Artemisia arborescens L essential oil into solid lipid nanoparticles (SLN). Two different SLN formulations were prepared following the high-pressure homogenization technique using Compritol 888 ATO as lipid and Poloxamer 188 or Miranol Ultra C32 as surfactants. The SLN formulation particle size was determined using Photon correlation spectroscopy (PCS) and laser diffraction analysis (LD). The change of particle charge was studied by zeta potential (ZP) measurements, while the melting and recrystallization behavior was studied using differential scanning calorimetry (DSC). In vitro release studies of the essential oil were performed at 35°C. Data showed a high physical stability for both formulations at various storage temperatures during 2 months of investigation. In particular, average diameter of Artemisia arborescens L essential oil-loaded SLN did not vary during storage and increased slightly after spraying the SLN dispersions. In vitro release experiments showed that SLN were able to reduce the rapid evaporation of essential oil if compared with the reference emulsions. Therefore, obtained results showed that the studied SLN formulations are suitable carriers in agriculture.

Solid Lipid Nanoparticle: A Review

“…Essential oil extracted from Artemisiaarboreseens L when incorporated in SLN, wereable to reduce the rapid evaporation comparedwith emulsions and the systems have been usedin agriculture as a suitable carrier of ecologicallysafe pesticides [26].…”

Evaluation of the Mosquito Repellent Activity of Nano-sized Microemulsion of Eucalyptus globulus Essential Oil Against Culicinae

“…Chemical instability, volatility, propensity for oxidation and poor water solubility of essential oils make them inconvenient for extensive use (8). Consequently, the incorporation of essential oils in nano-formulations, such as micro-emulsions, could solve these problems through increase in dissolution rate, water solubility, dispersion uniformity and stability after topical application (9). Micro-emulsions are transparent isotropic formulations, which are thermodynamically stable and are prepared by dispersion of two immiscible liquids (water and oil) containing appropriate amounts of surfactant.…”

Chemical Composition and Antibacterial Potential of Artemisia arborescens L. Essential Oil

“…The studies carried out on this species were mainly concerned about its phytochemical characteristics [1,29,30,32,33,39], but other aspects have been also considered, such as its genomics [19], its antiviral [43], antioxidant [11], anti-mycoplasmal [3] and allelochemical properties [14]. However, to our knowledge, no studies have been carried out on the antibacterial properties of EOs of this species.…”