Artemia salina Leach in photoprotection: A new model to evaluate the potential of nanoparticles for topical application

Gonçalo das Neves e Silva, Eullállia; Ferreira Barbosa, Gustavo Luis; Alves Confessor, Maine Virgínia; Bacalhau de Sousa, Wladymyr Jefferson; Lia Fook, Marcus Vinicius; Siqueira-Júnior, José P.; Pedro de Freitas, Luis Alexandre; Martins, Rodrigo Molina

doi:10.1016/j.jddst.2023.105164

Cited by 3 publications

(1 citation statement)

References 51 publications

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“…Considering the limited solubility of rutin in topical formulations and the possibility of negative interaction of bioactive compounds with organic filters, the encapsulation of rutin can be an interesting alternative to improve its benefits in photoprotective formulations, such as enhancing the photostability and safety of sunscreens. Also, by using rutin, the amount of chemical filters could be reduced in the formulation, which is an important approach to prevent adverse effects, toxicity, and also ecological impact [30,61,[96][97][98][99][100].…”

Section: Rutin and Sunscreen Systems: In Vitro And In Vivo Efficacy A...mentioning

confidence: 99%

Would be Rutin a Feasible Strategy for Environmental-Friendly Photoprotective Samples? A Review from Stability to Skin Permeability and Efficacy in Sunscreen Systems

Ariede,

Gomez Junior,

Cândido

et al. 2024

Preprint

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Rutin, a flavonoid compound found in various plants, has gained attention for its potential applications in the cosmetic industry due to its antioxidant, anti-inflammatory, and potential photoprotective properties. Our review explored the use of rutin (rutoside, 3-O-rutinoside-quercetin) in cosmetics/dermocosmetics, focusing on its physicochemical properties and stability, cutaneous permeability, and efficacy in sunscreen systems, involving in vitro tests and the current state of clinical trials. Rutin's ability to scavenge free radicals, prevent peroxidation, and reduce vascular fragility makes this flavonoid a promising ingredient for photoprotection. Studies have shown that rutin can enhance the sun protection factor (SPF) of sunscreen formulations, especially when combined with organic UV filters. The encapsulation of rutin in nanostructures has also been investigated to improve its applicability. Overall, rutin shows potential as a safe and effective ingredient in cosmetic/dermocosmetic formulations, offering protection against the harmful effects of UV radiation and oxidative stress on the skin.

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Section: Rutin and Sunscreen Systems: In Vitro And In Vivo Efficacy A...mentioning

confidence: 99%

Would be Rutin a Feasible Strategy for Environmental-Friendly Photoprotective Samples? A Review from Stability to Skin Permeability and Efficacy in Sunscreen Systems

Ariede,

Gomez Junior,

Cândido

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

Would Rutin be a Feasible Strategy for Environmental-Friendly Photoprotective Samples? A Review from Stability to Skin Permeability and Efficacy in Sunscreen Systems

Ariede,

Gomez Junior,

Cândido

et al. 2024

Cosmetics

View full text Add to dashboard Cite

Rutin, a flavonoid found in various plants, has gained attention for its potential applications in the cosmetic industry due to its antioxidant, anti-inflammatory, and potential photoprotective properties. Our review explored the use of rutin (rutoside, 3-O-rutinoside-quercetin) in cosmetics/dermocosmetics, focusing on its physicochemical properties and stability, cutaneous permeability, and efficacy in sunscreen systems, involving in vitro tests and the current state of clinical trials. Rutin’s ability to scavenge free radicals, prevent peroxidation, and reduce vascular fragility makes this flavonoid a promising ingredient for photoprotection. Studies have shown that rutin can enhance the sun protection factor (SPF) of sunscreen formulations, especially when combined with organic UV filters. The encapsulation of rutin in nanostructures has also been investigated to improve its applicability. Overall, rutin shows potential as a safe and effective ingredient in cosmetics/dermocosmetics, offering protection against the harmful effects of UV radiation and oxidative stress on the skin, as well as being a feasible strategy for developing environmentally friendly multifunctional sunscreens.

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Apple pomace extract: photochemopreventive action against UVA radiation in a cell culture model

Martins,

Barbosa

et al. 2024

Cuad. Ed. Desar.

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Apple pomace, a byproduct from juice industry, can be used as a valuable nutraceutical, hence its phenolic compounds, including rutin, are powerful antioxidants. This work evidence the extract enriched with apple polyphenols from apple pomace using ethanol: water as solvent and partitioned with ethyl acetate (1:1 w/w), where its lyophilized product was evaluated for its photochemopreventive action on MRC-5 fibroblasts against a harmful UVA radiation dose. The enriched apple pomace extract was able to promote photochemopreventive action against UVA radiation, decreasing cell death and the lipid peroxidation formation. Therefore, the optimized extraction process may make the apple pomace application viable as a source of bioactive extracts with photochemopreventive action against ultraviolet radiation to the use in dermal formulations.

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Artemia salina Leach in photoprotection: A new model to evaluate the potential of nanoparticles for topical application

Cited by 3 publications

References 51 publications

Would be Rutin a Feasible Strategy for Environmental-Friendly Photoprotective Samples? A Review from Stability to Skin Permeability and Efficacy in Sunscreen Systems

Would be Rutin a Feasible Strategy for Environmental-Friendly Photoprotective Samples? A Review from Stability to Skin Permeability and Efficacy in Sunscreen Systems

Would Rutin be a Feasible Strategy for Environmental-Friendly Photoprotective Samples? A Review from Stability to Skin Permeability and Efficacy in Sunscreen Systems

Apple pomace extract: photochemopreventive action against UVA radiation in a cell culture model

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