Artabotrys Hexapetalus (L. F.) Bhandari: A Plant With Enormous Biomedical Potential

Abstract

This review is intended to investigate the published report regarding phytochemical, ethnomedicinal, and pharmacological activities and put forth the therapeutic potential of Artabotrys hexapetalus (L. f.) Bhandari. (A. hexapetalus). It belongs to the family Annonaceae, one of the therapeutically important plants, broadly distributed throughout the world. An extensive review of the literature available in various recognized databases including logical writing and scientific literature, search engines such as Springerlink, ScienceDirect, SciFinder, PubMed, Scopus, Google Scholar, and BioMed Central as well as relevant books, websites, scientific publications, and dissertations were utilized as a source of information that provided an up-to-date review. Phytochemical profiling of these species revealed the presence of some imperative phytochemicals alkaloids, terpenoids, anthraquinones, butyrolactones, flavonoids, neolignans, phenolic compounds, and leucoanthocyanins as the basis of its valuable therapeutic properties. The other imperative phytoconstituents which contribute to the therapeutic properties are isoamericanin A, isoamericanol, americanin, artabotricinol and artabotriol, β-unsaturated-β-butyrolactones, arapetaloside taxifolin, apigenin-7-O-apiosylglucoside, glucoluteolin, and artabotrine. The pharmacological activities exhibited by Artabotrys hexapetalus as antimicrobial, antileishmanial, antioxidant, antifungal, antifertility, and anthelmintic properties are attributed to the presence of valuable bioactive phytoconstituents. Considering these facts an effort was made to present a comprehensive review enlightening the taxonomical, phytochemical, and pharmacological activities of plant Artabotrys hexapetalus. Future research can be directed to an extensive investigation about phytochemistry, clinical trials, pharmacokinetics, and acquiring safety data to add new dimensions to the therapeutic utilization of Artabotrys hexapetalus and other Artabotrys species.

Advocacy for the Medicinal Plant Artabotrys hexapetalus (Yingzhao) and Antimalarial Yingzhaosu Endoperoxides

“…A. uncinatus and A. odoratissimus in scientific communications. The plant has a large medicinal potential, well recognized in Asia, in particular for the treatment of parasitic diseases [ 127 ].…”

Complete chloroplast genome of Artabotrys hexapetalus (L.f.) Bhandari 1965 (Annonaceae)

“…family. A. hexapetalus is native to India and widely distributed in southern China (Puri 2020 ). Referred to as ‘Eagle’s Claw’ owing to the distinctive hook-like features on its involucral pedicel ( Figure 1C ), this plant serves both as an ornamental and trellis plant while also bearing significant economic value as a source of raw material for hemp ropes, paper, high-quality perfumes, soaps, and cosmetics.…”

In vitro and molecular docking of α-Glucosidase inhibitor potency from Artabotrys suaveolens leaf and stem bark

“…Artabotrys suaveolens is one of the species among Artabotrys, which is part of Annonaceae family, one of the largest plant family that has a lot of benefits from its parts [10]. This plant is widely distributed in southeast Asian countries (such as Indonesia, Malaysia, Thailand, Myanmar, and Philippine) until India [11].…”