Arsenic Through the Gastrointestinal Tract

Calatayud, Marta; Llopis, José Moisés Laparra

doi:10.1016/b978-0-12-418688-0.00010-1

Cited by 9 publications

(12 citation statements)

References 134 publications

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“…5). This indicates that health risks for the measured trace metals are unlikely in areas where fish consumption does not exceed the average per capita (Calatayud and Llopis 2015), the THQ values reported by Saria (2017) do not necessarily imply that As is likely to cause health risks to Blacktail snapper (Lutjanus fulvus), Indian Mackerel (Rastrelliger kanagurta) and Indian white shrimp (Fenneropenaeus indicus) consumers in the country. Apart from that, the high THQ values displayed by As and Cu (Fig.…”

Section: Public Health Implicationsmentioning

confidence: 93%

Bioaccumulation and public health implications of trace metals in edible tissues of the crustaceans Scylla serrata and Penaeus monodon from the Tanzanian coast

Rumisha

Leermakers

Mdegela

et al. 2017

Environ Monit Assess

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The coastal population in East Africa is growing rapidly but sewage treatment and recycling facilities in major cities and towns are poorly developed. Since estuarine mangroves are the main hotspots for pollutants, there is a potential for contaminants to accumulate in edible fauna and threaten public health. This study analysed trace metals in muscle tissues of the giant mud crabs (Scylla serrata) and the giant tiger prawns (Penaeus monodon) from the Tanzanian coast, in order to determine the extent of bioaccumulation and public health risks. A total of 180 samples of muscle tissues of S. serrata and 80 of P. monodon were collected from nine sites along the coast. Both species showed high levels of trace metals in the wet season and significant bioaccumulation of As, Cu and Zn. Due to their burrowing and feeding habits, mud crabs were more contaminated compared to tiger prawns sampled from the same sites. Apart from that, the measured levels of Cd, Cr and Pb did not exceed maximum limits for human consumption. Based on the current trend of fish consumption in Tanzania (7.7 kg/person/year), the measured elements (As, Cd, Co, Cu, Mn, Pb and Zn) are not likely to present health risks to shellfish consumers. Nevertheless, potential risks of As and Cu cannot be ruled out if the average per capita consumption is exceeded. This calls for strengthened waste management systems and pollution control measures.

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Section: Public Health Implicationsmentioning

confidence: 93%

Bioaccumulation and public health implications of trace metals in edible tissues of the crustaceans Scylla serrata and Penaeus monodon from the Tanzanian coast

Rumisha

Leermakers

Mdegela

et al. 2017

Environ Monit Assess

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“…Predictably, the Cd, Pb, Cr, and As concentrations were found below toxic limits, 9, 9, 7 and 7 fold below than toxic threshold, respectively [48][49][50][51], including the As values obtained in Basmati variety in cooked rice (increased 10 fold). Concentrations equal to the Limit of Quantification (LOQ) were assumed for Cd, Pb, Cr, and As in the worst scenario.…”

Section: Metalllic and Metalloid Content In Ricementioning

confidence: 88%

Nutritional Quality of the Most Consumed Varieties of Raw and Cooked Rice in Spain Submitted to an In Vitro Digestion Model

Aguilera-Velázquez

Carbonero

Martín-Carrasco

et al. 2021

Foods

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Rice is one of the most consumed staple foods around the world and its trade is highly globalized. Increased environmental pollution generates a large amount of waste that, in many cases, is discarded close to culture fields. Some species are able to bioaccumulate toxic substances, such as metals, that could be transferred to the food chain. The main goal of this study was to evaluate the content of metallic (Al, Cd, Pb, and Cr) and metalloid elements (As) in 14 of the most consumed varieties of rice in Spain and their effects on human health. The samples were cooked, and human digestion was simulated by using a standard in vitro digestion method. Metallic and metalloid element levels were analysed by Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES), previous called microwave digestion. Both the human health risk index, Hazard Quotient, and Lifetime Cancer Risk did not show toxic values in any case. Rice with a higher non-digestible fraction showed a higher liberation of proteins and a lower glycemic index. There were no significant differences in the concentrations of metallic and metalloid elements in cooked rice or in the digestible fraction in all varieties analysed. However, Al concentrations were higher than other metals in all varieties studied due to its global distribution. No relationship has been observed between the digestibility of rice and the bioaccessibility of each metallic and metalloid element. All of the studied rice varieties are healthy food products and its daily consumption is safe. The regular monitoring of metals and As in rice consumed in Spain may contribute to improvements in the human health risk evaluation.

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“…This is possibly because the Pb released from organic complexes precipitate at the intestinal pH (Ruby et al 1993, 1999, Li et al 2014). However, Pb (II) can be bio-transformed, modifying its solubility and toxicity (Calatayud andLlopis 2015, Cangelosi et al 2017).…”

Section: Pbmentioning

confidence: 99%

“…Several toxic arsenic species may form in the intestine because of the reaction between arsenic and food compounds. (Conrad and Barton 1978, Mushak 1991, Diamond et al 1998, Calatayud and Llopis 2015, Ollson et al 2017 The damages caused by arsenic are classified as carcinogenic, mutagenic, or genotoxic, producing immunological, reproductive, developmental, neurological, renal, hepatic, hematological, gastrointestinal, cardiovascular, pulmonary, respiratory, and dermal harm (Mandal andSuzuki 2002, Sattar et al 2016). Pb is classified as "probably carcinogenic to humans" (Group 2A), according to IARC (2006).…”

Section: Introductionmentioning

confidence: 99%

Arsenic and Lead Bioaccessibilities Measured With a Novel Reactor System Using the Mexican Standard and Pbet Methods: Comparison With in Vivo and in Vitro Reported Data

García-Rodríguez

Gutiérrez-Ruíz

Ceniceros‐Gómez

2021

RICA

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Contaminated soils can become exposure routes of elements toxic to human beings. The health risk of a toxic element by ingestion depends on its bioavailability in the gastrointestinal system, measured in vivo or in vitro. This study aimed to use a novel, versatile reactor (gastrointestinal simulation reactor system to determine bioaccessibility -GSRSB-) to measure lead and arsenic bioaccessibility in the gastric and intestinal phases by applying a modified physiologically based extraction test (PBET). Three composite samples of polluted soils with As (0.50 - 3.25%) and Pb (0.02 - 0.10%) and the certified reference material NIST 2710 were analyzed with this GSRSB-PBET method and the NOM-147 Mexican standard method, which uses an end-over-end shaker. All results were compared to one another. The NIST 2710 results were contrasted with those reported in vivo and in vitro by 14 laboratories. The (GSRSB-PBET) gastric phase ranges were 35.9-55.1 % (As) and 59.6-96.1 % (Pb), while (NOM-147) gastric phases were 35.8-60.4 % (As) and 61.0-70.7 % (Pb). The (GSRSB-PBET) intestinal phase ranges were 39.5-46.9 % (As) and 19.9-31.5 % (Pb). The As and Pb compounds and the stirring technique seem to influence bioaccessibility. On the other hand, the comparison of NIST 2710 results with those reported in vitro and in vivo indicated that As and Pb gastric bioaccessibility obtained with GSRSB-PBET falls into the in vivo results range, while NOM-147 results are higher and fall outside the in vivo range, possibly overestimating the risk. Thus, the proposed method is adequate for modifying the current Mexican Standard Method (NOM-147), which only allows the calculation of Pb gastric bioavailability in vitro.

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Arsenic Through the Gastrointestinal Tract

Cited by 9 publications

References 134 publications

Bioaccumulation and public health implications of trace metals in edible tissues of the crustaceans Scylla serrata and Penaeus monodon from the Tanzanian coast

Bioaccumulation and public health implications of trace metals in edible tissues of the crustaceans Scylla serrata and Penaeus monodon from the Tanzanian coast

Nutritional Quality of the Most Consumed Varieties of Raw and Cooked Rice in Spain Submitted to an In Vitro Digestion Model

Arsenic and Lead Bioaccessibilities Measured With a Novel Reactor System Using the Mexican Standard and Pbet Methods: Comparison With in Vivo and in Vitro Reported Data

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