Arsenic detection in water using microfluidic detection systems based on the leucomalachite green method

Lace, Annija; Ryan, David; Bowkett, Mark; Cleary, John

doi:10.1039/c9ay01580a

Cited by 12 publications

(11 citation statements)

References 63 publications

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“…Lace and co-workers developed a method for microfluidic detection of arsenic in water using leucomalachite green dye [65,66]. The dye reacted with arsenic to produce a green coloured complex with peak absorption (λ max ) at 617 nm.…”

Section: Absorbance Based Detectionmentioning

confidence: 99%

A Review of Microfluidic Detection Strategies for Heavy Metals in Water

Lace

Cleary

2021

Chemosensors

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Heavy metal pollution of water has become a global issue and is especially problematic in some developing countries. Heavy metals are toxic to living organisms, even at very low concentrations. Therefore, effective and reliable heavy metal detection in environmental water is very important. Current laboratory-based methods used for analysis of heavy metals in water require sophisticated instrumentation and highly trained technicians, making them unsuitable for routine heavy metal monitoring in the environment. Consequently, there is a growing demand for autonomous detection systems that could perform in situ or point-of-use measurements. Microfluidic detection systems, which are defined by their small size, have many characteristics that make them suitable for environmental analysis. Some of these advantages include portability, high sample throughput, reduced reagent consumption and waste generation, and reduced production cost. This review focusses on developments in the application of microfluidic detection systems to heavy metal detection in water. Microfluidic detection strategies based on optical techniques, electrochemical techniques, and quartz crystal microbalance are discussed.

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Section: Absorbance Based Detectionmentioning

confidence: 99%

A Review of Microfluidic Detection Strategies for Heavy Metals in Water

Lace

Cleary

2021

Chemosensors

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“…Similar enzyme inhibition by copper metal ions has been reported by Male and coauthors [39] where he has observed its interference in different levels. Lace and coauthors [5] has reported that Fe 2+ ions above 0.1 mg -1 interfere with As 3+ monitoring using the microfluidic detection system.…”

Section: Effect Of Interfering Substancesmentioning

confidence: 99%

“…[4]. Exposure to arsenic can lead to various health concerns including cardiovascular diseases [5], skin lesions [6], arsenicosis [7], various types of cancer and mutagenic effects, hematological side effects [8], hyperkeratosis [9], and many more disorders. Arsenic is registered as priority toxic element under the European Directive on Environmental Quality Standards due to its toxicity [5].…”

Section: Introductionmentioning

confidence: 99%

Reusable Enzymatic Strip for Detection of Arsenic

Hooda

Verma

Gahlaut

et al. 2021

Braz. arch. biol. technol.

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Arsenic is considered as one of the highly hazardous elements in the environment and a serious carcinogen for the human health. More attention has taken towards the arsenic due to its presence in ground water in India, China, Bangladesh, Inner Mongolia and several other regions of the world. It's been a challenge to remove arsenic due to the lack of its efficient detection approach in the complicated environmental matrix. The proposed method describes an enzymatic method for arsenic determination using arsenite oxidase, which catalyzes the oxidation of arsenite to arsenate. Hence, a colorimetric PVC strip with immobilized arsenite oxidase has been developed to detect the arsenic concentration and also having potential for the field-testing. The influence of the optimal conditions i.e. pH, temperature, storage stability, and reusability of free and immobilized enzyme were evaluated and compared. The results have shown that the stabilities were significantly enhanced compared with free counterpart. Residual activity of the immobilized enzyme was 43% of the initial activity after being recycled 10 times. We approve that this novel low cost immobilized carrier presents a new approach in large scale applications and expected to act as a model for establishment of indigenous arsenic sensor in miniature form.

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“…However, both of them require tedious sample preparation and pretreatment, expensive equipment, and professional personnel, making them insuitable in applications for autonomous, in situ, and continuous monitoring of heavy metals. In this case, ocean monitoring sensors based on colorimetric, fluorescent, and chemiluminescent methods appear as promising technologies due to the high sensitivity and feasibility, versatility, and reproducibility [84][85][86][87][88][89][90][91][92][93][94][95], and all of these methods have been truly applied for online analysis of heavy metals in seawater.…”

Section: Heavy Metalsmentioning

confidence: 99%

“…With this portable device, 12 samples of Fe(II) and 6 samples of Mn could be analyzed per hour with LODs of 27 nM and 28 nM, and precisions of 2.1% and 2.4% (n = 19), respectively. Lace et al reported an innovative optofluidics system for monitoring of arsenic in water with the leucomalachite green dye method [91]. The principle involves the reactions of arsenic and potassium iodate under acidic conditions, and leucomalachite green is oxidized to malachite green by the liberated iodine, producing a green color with an absorption peak at 617 nm.…”

Section: Heavy Metalsmentioning

confidence: 99%

Autonomous and In Situ Ocean Environmental Monitoring on Optofluidic Platform

et al. 2020

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Determining the distributions and variations of chemical elements in oceans has significant meanings for understanding the biogeochemical cycles, evaluating seawater pollution, and forecasting the occurrence of marine disasters. The primary chemical parameters of ocean monitoring include nutrients, pH, dissolved oxygen (DO), and heavy metals. At present, ocean monitoring mainly relies on laboratory analysis, which is hindered in applications due to its large size, high power consumption, and low representative and time-sensitive detection results. By integrating photonics and microfluidics into one chip, optofluidics brings new opportunities to develop portable microsystems for ocean monitoring. Optofluidic platforms have advantages in respect of size, cost, timeliness, and parallel processing of samples compared with traditional instruments. This review describes the applications of optofluidic platforms on autonomous and in situ ocean environmental monitoring, with an emphasis on their principles, sensing properties, advantages, and disadvantages. Predictably, autonomous and in situ systems based on optofluidic platforms will have important applications in ocean environmental monitoring.

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Arsenic detection in water using microfluidic detection systems based on the leucomalachite green method

Abstract: This work describes the first use of microfluidic detection technology for arsenic detection in water using leucomalachite green dye.

Cited by 12 publications

References 63 publications

A Review of Microfluidic Detection Strategies for Heavy Metals in Water

A Review of Microfluidic Detection Strategies for Heavy Metals in Water

Reusable Enzymatic Strip for Detection of Arsenic

Autonomous and In Situ Ocean Environmental Monitoring on Optofluidic Platform

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