Arsenic bioleaching in medical realgar ore and arsenicbearing refractory gold ore by combination of &lt;i&gt;Acidithiobacillus ferrooxidans&lt;/i&gt; and &lt;i&gt;Acidithiobacillus thiooxidans&lt;/i&gt;

Leng, Feifan; Sun, Shangchen; Wang, Yonggang; Jing, Yanjun; Wei, Qingwei; Li, Hongyu

doi:10.4314/tjpr.v15i5.19

Cited by 2 publications

(2 citation statements)

References 17 publications

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“…When the multiplication of bacteria reach to the plateau phase transfer them to fresh media containing a higher concentration of realgar [ 46 ]. After approximately 2 months domesticated, the arsenic resistance of the bacterium increased substantially [ 50 ].…”

Section: Bioleaching Of Realgar By a Ferrooxidansmentioning

confidence: 99%

Properties of realgar bioleaching using an extremely acidophilic bacterium and its antitumor mechanism as an anticancer agent

Chen

Yan

et al. 2017

Biol Res

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Realgar is a naturally occurring arsenic sulfide (or Xionghuang, in Chinese). It contains over 90% tetra-arsenic tetra-sulfide (As4S4). Currently, realgar has been confirmed the antitumor activities, both in vitro and in vivo, of realgar extracted using Acidithiobacillus ferrooxidans (A. ferrooxidans). Bioleaching, a new technology to greatly improve the use rate of arsenic extraction from realgar using bacteria, is a novel methodology that addressed a limitation of the traditional method for realgar preparation. The present systematic review reports on the research progress in realgar bioleaching and its antitumor mechanism as an anticancer agent. A total of 93 research articles that report on the biological activity of extracts from realgar using bacteria and its preparation were presented in this review. The realgar bioleaching solution (RBS) works by inducing apoptosis when it is used to treat tumor cells in vitro and in vivo. When it is used to treat animal model organisms in vivo, such as mice and Caenorhabditis elegans, tumor tissues grew more slowly, with mass necrosis. Meanwhile, the agent also showed obvious inhibition of tumor cell growth. Bioleaching technology greatly improves the utilization of realgar and is a novel methodology to improve the traditional method.

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Section: Bioleaching Of Realgar By a Ferrooxidansmentioning

confidence: 99%

Properties of realgar bioleaching using an extremely acidophilic bacterium and its antitumor mechanism as an anticancer agent

Chen

Yan

et al. 2017

Biol Res

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“…This process has been successfully utilized for gold processing in both laboratory investigations and industrial scale operations [1][2][3][4]. Refractory arsenic-bearing ores are toxic to microorganisms, so mixed cultures of iron-and sulfur-oxidizing microorganisms are usually used for the pretreatment [5,6]. Optimising the influence of chemical and physicochemical parameters such as pH, nutrient medium type, oxygen, and carbon dioxide supply, temperature are the main concerns which need to be evaluated in biooxidation stage [7].…”

Section: Introductionmentioning

confidence: 99%

Biooxidation of a High-Grade Arsenopyritic Gold Ore Using a Mixed Culture of Moderate Thermophilic Microorganisms

Abdolahi

Ahmadi

Zilouei

et al. 2017

SSP

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This study investigated the biooxidation of a high-grade refractory gold ore from the Zarshouran mine (West Azarbaijan, Iran) in shake flasks and a stirred tank bioreactor (STBR) using a mixed culture of moderately thermophilic microorganisms. The influence of four critical parameters including, pH, biooxidation time, nutrient medium type and pulp density on the iron and arsenic extraction as well as gold cyanidation were evaluated in a full factorial design in shake flasks at 45 °C. Maximum iron extraction was obtained in M9K medium, pulp density of 5% (w/v), 15 days of biooxidation time and the pH of 1.6. Biooxidation in the STBR was carried out at the pulp densities of 10% and 20% (w/v), the pH of 1.7 in the M9K medium, in which dissolved oxygen, pH, redox potential, iron and arsenic concentrations were measured during the process. It was found that 61% decrement of sulphur content in the STBR led to recover 80% of gold, which was 43% higher than that in the conventional cyanidation process. It can be concluded that the oxidation of refractory arsenopyrite gold ore can achieved using a moderately thermophilic biooxidation culture.

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Arsenic bioleaching in medical realgar ore and arsenicbearing refractory gold ore by combination of <i>Acidithiobacillus ferrooxidans</i> and <i>Acidithiobacillus thiooxidans</i>

Cited by 2 publications

References 17 publications

Properties of realgar bioleaching using an extremely acidophilic bacterium and its antitumor mechanism as an anticancer agent

Properties of realgar bioleaching using an extremely acidophilic bacterium and its antitumor mechanism as an anticancer agent

Biooxidation of a High-Grade Arsenopyritic Gold Ore Using a Mixed Culture of Moderate Thermophilic Microorganisms

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