Arrhythmogenic right ventricular dysplasia demonstrated by phase mapping of gated equilibrium radioventriculography

Bourguignon, M.; Sébag, C; Guludec, Dominique Le; Davy, Jean‐Marc; Laine, J F; Slama, Michel; Motté, G; Syrota, A.

doi:10.1016/0002-8703(86)90656-3

Cited by 18 publications

(7 citation statements)

References 6 publications

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“…Either LVEF or RVEF were significantly reduced during the arrhythmia, in keeping with previous reports [11][12][13][14], However, these changes prevented the origin of VT from being predicted in only 2 of 10 subjects.…”

Section: Discussionsupporting

confidence: 91%

“…Bourghuignon et al [ 14] described 1 case of ARVD in whom phase imaging correctly localized the focus of the arrhythmia in the right ventricular infundibulum ac cording to endocardial catheter mapping.…”

Section: Resultsmentioning

confidence: 99%

“…Sequential regional phase mapping of radionuclide gated blood pool scintigraphy has become a widely used technique for noninvasive assessment of regional ven bundle branch block [4][5][6][7], Wolff-Parkinson-White syn drome [5,8] and artificial pacing [9], The ability of this technique to detect abnormal foci of electrical activation has been assessed in patients with ectopic ventricular beats [10] and sustained ventricular tachycardia (VT) [11][12][13][14], It has been reported that phase mapping of VT pro vides noninvasive data consistent with the electrophy siologic characteristics of this arrhythmia [11][12][13]. How ever, few data are still available on the correlation between phase mapping and the conventional electrical mapping in patients with VT [12][13][14] and controversy still exists about the actual role of radionuclide studies in this particular setting.…”

Section: Introductionmentioning

confidence: 99%

“…How ever, few data are still available on the correlation between phase mapping and the conventional electrical mapping in patients with VT [12][13][14] and controversy still exists about the actual role of radionuclide studies in this particular setting.…”

Section: Introductionmentioning

confidence: 99%

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Radionuclide Phase Imaging of Ventricular Tachycardia

Verna¹,

Casucci²,

S³

et al. 1989

Am J Noninvas Cardiol

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The emptying sequence of ventricular blood pool was studied by scintigraphic regional phase mapping in 10 patients with monomorphic and sustained ventricular tachycardia (VT) and compared to an electrophysiological study in order to assess the scintigraphic accuracy for the noninvasive localization of abnormal site of activation. All patients underwent both phase imaging and electrical mapping studies. There were 6 coronary artery disease patients, 3 patients with arrhythmogenic right ventricular disease and 1 patient with dilatative cardiomyopathy. Phase image studies were performed by first harmonic Fourier analysis of radionuclide angiography either during sinus rhythm or during spontaneous or catheter-induced VT. Eleven morphologically distinct VTs with a heart rate ranging from 145 to 260 beats min^-1 (mean 173 ± 32 beats min^-1) were imaged. Endocardial catheter mapping was accomplished in 9 different VT morphologies. Three patients also had epicardial intraoperative mapping. The site of origin of VT by a scintigraphic method was defined as the area of earliest regional contraction on the biventricular scintigram. By separating the right ventricle into 5 segments and the left ventricle into 7 segments, with multiple view cardiac imaging, a close correspondence between the site of origin determined by electrophysiological study and the region of earliest emptying of radioactivity was observed in 7 of 9 (77%) VTs. In 2 patients the extension of regional akinesia during VT prevented us from an accurate mapping of the regional time sequence of contraction. Scintigraphic phase mapping has inherent limitations due to wall motion dependency and relatively low resolution power but it is feasible in selected patients with monomorphic, inducible and long-sustained VT in whom adequate time for data collection is provided. In this subset of patients the site of origin of VT could be localized on a 'segmental' basis with close correspondence to electrophysiological mapping studies.

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Section: Discussionsupporting

confidence: 91%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Radionuclide Phase Imaging of Ventricular Tachycardia

Verna¹,

Casucci²,

S³

et al. 1989

Am J Noninvas Cardiol

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“…This fact is consistent with previous electrophysiologic and scintigraphic reports [2,26] concerning VT related to LV aneurysm, originating from the border zone of dyskinesia. Fewer reports are available concerning VT related to ARVD [21][22][23][24]; our findings suggest -for the first time with GERV -that such a spatial relationship could also hold true for right ventricular dyskinesia. In 5/6 patients, VT-phase mapping was consistent with VT-QRS pattern, and with endocardial mapping of right ventricle in the only patient in which it was performed.…”

Section: A) Ventricular Tachycardiasupporting

confidence: 53%

Phase mapping of radionuclide gated biventriculograms in patients with sustained ventricular tachycardia or Wolff-Parkinson-White syndrome

et al. 1987

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Accuracy of Fourier phase mapping of radionuclide gated biventriculograms in detecting the origin of abnormal ventricular activation was studied during ventricular tachycardia or preexcitation. Group I included six patients suffering from clinical recurrent VT; 3 gated blood pool studies were acquired for each patient: during sinus rhythm, right ventricular pacing, and induced sustained VT-Group II included seven patients with Wolff-Parkinson-White syndrome and recurrent paroxysmal tachycardia; 3 gated blood pool studies were acquired for each patient: during sinus rhythm, right atrial pacing and orthodromic reciprocating tachycardia. Each acquisition lasted 5 min, in 30 degrees-40 degrees left anterior oblique projection. In Group I, the Fourier phase mapping was consistent with QRS morphology and axis during VT (5/6), except in one patient with LV aneurysm and LBBB electrical pattern during VT. Origin of VT on phase mapping was located in the right ventricle (n = 2) or in left ventricle (n = 4), at the border of wall motion abnormalities each time they existed (5/6). In Group II, the phase advance correlated with the location of the accessory pathway determined by ECG and endocardial mapping (n = 6) and per-operative epicardial mapping (n = 1). Discrimination between anterior and posterior localisation of paraseptal pathways and location of intermittent preexcitation was not possible. We conclude that Fourier phase mapping is an accurate method for locating the origin of VT and determining its etiology. It can help locate the site of ventricular preexcitation in patients with only one accessory pathway; its accuracy in locating multiple accessory pathways remains unknown.

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