Arrhythmias during Halothane Anesthesia I: The Influence of Atropine During Induction with Intubation

Eikard, B.; Sørensen, B.

doi:10.1111/j.1399-6576.1976.tb05042.x

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1986

1995

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Cited by 16 publications

(3 citation statements)

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“…Sixty-one patients were given gen¬ eral anesthesia by Venturi jet ventila¬ tion, 25 by endotracheal intubation, one by nasotracheal intubation, and seven by previous tracheotomy. Six patients were examined under local anesthesia with prior topical spray and transtracheal block.…”

Section: Resultsmentioning

confidence: 99%

Cardiac Complications of Suspension Laryngoscopy: Fact or Fiction?

Wenig¹,

Raphael

Stern

et al. 1986

Archives of Otolaryngology - Head and Neck Surgery

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Section: Resultsmentioning

confidence: 99%

Cardiac Complications of Suspension Laryngoscopy: Fact or Fiction?

Wenig¹,

Raphael

Stern

et al. 1986

Archives of Otolaryngology - Head and Neck Surgery

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“…Atropine has been shown to increase the incidence of cardiac arrhythmia during induction of anaesthesia [3]. In addition, i.v.…”

Section: Commentmentioning

confidence: 99%

“…Cardiac arrhythmia has been reported after administration of atropine during induction of anaesthesia [3]. This may result from reduction in vagal protection and prolongation of the QT interval.…”

mentioning

confidence: 99%

Effect of Atropine on the Qt Interval and T-Wave Amplitude in Healthy Volunteers

Annila

Yli‐Hankala

Lindgren

1993

British Journal of Anaesthesia

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Prolongation of the QT interval of the ECG represents an imbalance in cardiac autonomic function and may predict cardiac arrhythmia. Vagal activity protects against prolongation of the QT interval which may be associated with flattening of the T-wave of the ECG. The changes in QT interval, T-wave amplitude and respiratory sinus arrhythmia (RSA) were studied after i.v. administration of atropine 20 micrograms kg-1 or placebo to 10 healthy volunteers in a cross-over study. After atropine, a decrease in RSA occurred in all volunteers, but remained at baseline values after placebo. Corrected QT interval (QTc) increased from 410 (20) ms to 454 (11) ms (P < 0.001) 5 min after atropine and remained prolonged for the entire study period (60 min). The T-wave flattened significantly (measured as R:T ratio) up to 30 min, without any changes in the R-wave. No changes in the ECG occurred with placebo.

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