“…3 In conscious dogs, SB can be associated with physiologic and pathological conditions, such as hypothermia, hypoxia, hyperkalemia, or any increase in vagal tone (attributable to vagal reflexes, intestinal obstruction, urethral obstruction, or intracranial mass). [3][4][5] Other causes known to decrease heart rate are related to administra- tion of drugs, such as digoxin, β-adrenoceptor antagonists, calcium channel blockers, or lidocaine. In dogs with marked SB secondary to vagotonia (vagal maneuvers), a sinus arrhythmia may be present with normal PQRS-T intervals and variation in P-P intervals.…”