“…3AB‐OS cells also showed monosomies, trisomies and nullisomies, together with 32 unidentifiable marker chromosomes, and they exhibited 49 CNVs (gains/losses), spanning almost all the chromosomes. Remarkably, the abnormalities evidenced in 3AB‐OS cells appear to be strongly congruent with abnormalities described in the literature in a large number of pediatric and adult osteosarcomas (Bridge et al, 1997; Batanian et al, 2002; Niini et al, 2011), which have shown a karyotype ranging from haploid to near hexaploid, with structural abnormalities involving the chromosomal regions 1p11–13, 4q27–33, 6p23–25, 6q16–25, 7q11–36, 11p10–15, 11q23, and 17p11.2–13. Moreover, 3AB‐OS cells showed losses/gains in agreement with those seen in osteosarcoma patients (Bridge et al, 1997; Batanian et al, 2002; Niini et al, 2011), such as losses at chromosome arms 8p, 9p, 16p, 3q, 13q, and gains at chromosome arms 6p, 8q, 12p, 14q, 17p, and 20q.…”