Aromatic Constituents from<i>Vladimiria souliei</i>

Tan, Ren Xiang; Jakupovic, J.; Jia, Zhuo

doi:10.1055/s-2006-961015

Cited by 55 publications

(28 citation statements)

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“…This crude extract was subjected repeatedly to column chromatography on Si gel, Sephadex LH-20, RP-18 and preparative HPLC to afford compounds 1-6 (Figure 1), including two new phenolic compounds, gramniphenol A and B (1-2), together with four known phenols, 9'-dehydroxy-vladinol F (3), 6 vladinol F (4), 7 9-O-β-D-xylopyranoside-vladinol F (5), 8 and 4,9-dihydroxy-4',7-epoxy-8',9'-dinor-8,5'-neolignan-7'-oic acid (6). 9 The structures of the compounds 1-6 were as shown in Figure 1, and the NMR data of 1 and 2 were listed in Table 1 ) could also be observed in its IR spectrum.…”

Section: Resultsmentioning

confidence: 99%

Phenolic Compounds from Arundina graminifolia and Their Anti-Tobacco Mosaic Virus Activity

Liu¹,

Shen²,

Shu³

et al. 2012

Bulletin of the Korean Chemical Society

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Section: Resultsmentioning

confidence: 99%

Phenolic Compounds from Arundina graminifolia and Their Anti-Tobacco Mosaic Virus Activity

Liu¹,

Shen²,

Shu³

et al. 2012

Bulletin of the Korean Chemical Society

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“…Although chemical marker(s) have been employed to evaluate the qualities of Radix Aucklandiae [12], Radix Vladimiriae [13,14], Radix Inulae [15,16], and Radix Aristolochiae [17,18], there lacks a comprehensive study on the authentication of Radix Aucklandiae and its common substitutes. Here, we report the authentication of Radix Aucklandiae, Radix Aladimiriae, Radix Inulae, and Radix Aristolochiae by comparison of chemical profiles of the essential oils generated by GC-MS with hierarchical clustering analysis.…”

Section: Introductionmentioning

confidence: 99%

Authentication of Radix Aucklandiae and its substitutes by GC‐MS and hierarchical clustering analysis

Shum

Chen

et al. 2007

J of Separation Science

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Radix Aucklandiae (Muxiang in Chinese), the dried root of Aucklandia lappa, is used as a medicinal material for digestive system disorders in traditional Chinese medicine for centuries. Owing to the similarity of morphologies and trade names, Radix Vladimiriae (Chuan-Muxiang), the roots of Vladimiria souliei and V. souliei var. cinerea, and Radix Inulae (Tu-Muxiang), the roots of Inula helenium and Inula racemosa, as well as the renal toxic aristolochic acid containing Radix Aristolochiae (Qing-Muxiang), the roots of Aristolochia debilis and Aristolochia contorta, are often used confusedly as the substitutes of Radix Aucklandiae. In order to ensure the effective and safe utility of Radix Aucklandiae, a GC-MS method was developed to generate the chemical profiles of essential oils of Radix Aucklandiae and its substitutes. In addition, hierarchical clustering analysis was used to compare the similarities of these chemical profiles. It was found that all the samples of A. lappa have similar chemical profiles and were clustered into one group, while the samples of Radix Vladimiriae, Radix Inulae, and Radix Aristolochiae were clustered into their own independent groups, respectively, suggesting that together with hierarchical clustering analysis, chemical profiles of essential oils generated by GC-MS could objectively discriminate Radix Aucklandiae from its common substitutes.

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“…foedidum was successively subjected to silica gel and Sephadex LH-20 column chromatography as well as semipreparative HPLC to afford 10 lignans (1-10). Compounds 5-10 were identified as prinoresinol (5), 13) syringaresinol (6), 14) olivil (7), 15) 4,4Ј,7,7Ј-tetrahydroxy-3,3Ј-dimethoxy-9,9Ј-epoxylignan (8), 16) 4,4Ј,8,9-texahydroxy-3,3Ј-dimethoxy-7,9Ј-epoxylignan (9), 17) and padocin (10), 18) respectively, based on comparisons of their spectral data with those already reported. 13) The clearest differences between compound 1 and lariciresinol were less CH, a more oxygenated quaternary carbon (d 71.4), and an obvious upfield shift of C-9 in 1.…”

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Four New Lignans from Viburnum foetidum var. foedidum

Chen

et al. 2009

CHEMICAL & PHARMACEUTICAL BULLETIN

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NotesPlants of the Viburnum genus, which belong to the family Caprifliaceae, comprise about 230 species and are mainly distributed in Asia and South America. China has more than 70 species.1) The use of Viburnum species in Chinese popular folk medicine has a long history. For example, the leaves and skins of V. cylindricum, called shuihongmu in China, are used for the treatment of cough, diarrhea, rheumatoid arthritis, and tumefaction.2) V. odoratissimum, commonly known as shanhushu, is used for tumefaction and bone fractures. 3)Phytochemical studies revealed that Viburnum species mainly contain triterpenoids, 4,5) iridoids, 6) vibsane-type diterpenes, 7,8) lignans, 9) and phenolic glycosides. 10) Vibsane-type diterpenes are an unusual group of natural products, which can be subdivided into three classes consisting of sevenmembered ring, eleven-membered ring, and rearranged types.1) These diterpenoids have interesting biological activities such as piscicidal activity, plant growth regulatory activity, and cytotoxic activity. 11,12) As a part of our search for new vibsane-type diterpenoids, the 70% aqueous acetone extract of the aerial part of the V. foetidum var. foedidum from Simao County, Yunnan Province, P. R. China, was investigated phytochemically. Four new lignans (1-4) together with six known ones were found. The isolation and structural elucidation of the four new lignans are reported here. Results and DiscussionThe 70% aqueous acetone extract of the aerial parts of V. foetidum var. foedidum was successively subjected to silica gel and Sephadex LH-20 column chromatography as well as semipreparative HPLC to afford 10 lignans (1-10). Compounds 5-10 were identified as prinoresinol (5), 13) syringaresinol (6), 14) olivil (7), 15) 4,4Ј,7,7Ј-tetrahydroxy-3,3Ј-dimethoxy-9,9Ј-epoxylignan (8), 16) 4,4Ј,8,9-texahydroxy-3,3Ј-dimethoxy-7,9Ј-epoxylignan (9), 17) and padocin (10), 18) respectively, based on comparisons of their spectral data with those already reported. 13) The clearest differences between compound 1 and lariciresinol were less CH, a more oxygenated quaternary carbon (d 71.4), and an obvious upfield shift of C-9 in 1. Considering the characteristic NMR spectrum discussed above and the fact that 1 had an additional more ring system compared with that of lariciresinol, 1 was deduced to be 8,9-epoxy-lariciresinol. The formation of 8,9-epoxy led to the upfield shift of C-9 and the presence of an oxygenated quaternary carbon (d 71.4).In the rotating frame Overhauser enhancement spectroscopy (ROESY) of 1, the correlation of H-7 with H-8Ј indicated that both H-7 and H-8Ј were in the b-orientation. However, the ROESY spectrum could not provide sufficient information to elucidate the stereochemistry of C-8. After many attempts with different solvents, a single crystal of 1 was obtained in MeOH-H 2 O (95 : 5). A single crystal X-ray analysis clarified the relative configuration of C-8 and unambiguously confirmed the structure of 1 (Fig. 1).Compound 2, a white amorphous powder, had the molecu- The 70% aqueous a...

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Aromatic Constituents fromVladimiria souliei

Cited by 55 publications

References 1 publication

Phenolic Compounds from Arundina graminifolia and Their Anti-Tobacco Mosaic Virus Activity

Phenolic Compounds from Arundina graminifolia and Their Anti-Tobacco Mosaic Virus Activity

Authentication of Radix Aucklandiae and its substitutes by GC‐MS and hierarchical clustering analysis

Four New Lignans from Viburnum foetidum var. foedidum

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