Aristolactam derivatives from Fissistigma glaucescens

The isolation-biological activities (2014–2022), bio, semi, total synthesis (1978–2022) and SAR studies of a potential naturally engineered scaffold aristolactam

“…35). 65 In addition to aristolactam AIb 102 , eleven others known aristolactam derivatives were isolated in this work, including aristolactam AIIa 88 , aristolactam E 103 , aristolactams AIa 89 , velutinam 46 , enterocarpam II 98 , aristololactam GII 104 , goniothalactam 105 , aristololactam BIII 80 , aristololactam BII 44 , aristololactam AII 43 , and piperolactam A 50 . To the best of the author's knowledge, this was the first report to observe aristolactam AIb 102 , aristolactam AIIa 88 , aristolactam E 103 , aristolactam AIa 89 , and enterocarpam II 98 in the genus Fissistigma , as well as aristolactam AIb 102 , and aristolactam E 103 in the family Annonaceae .…”

“…35). 65 36). 66 In their cytotoxicity evaluation, they exhibited significant cytotoxicity against HK-2 cells.…”