The covid-19 pandemic affects the world. It has spread to more than 200 countries and threatens the lives of millions. Diabetes affects people all over the world, especially in developing countries. Nowadays, diabetes and COVID-19 are major global health concerns. Evidence regarding the impact of diabetes and COVID-19 is limited in the literature. It is unclear whether or not people with diabetes have an increased tendency toward COVID-19. However, risk factors lead to higher mortality rates among patients with diabetes and COVID-19. The physiological and immunological parameters involved in the current study included high sensitivity to CRP (Hs-CRP), fasting blood sugar (FBS), insulin, Homo IR, and interleukin-10 (IL-10). A spectrophotometer analyzed FBS, while ELISA performed other parameters. The results showed a significant increase in all immunological and physiological parameters of patients compared with the control group in both categories of total comparison and sex comparison. In the same way, the results recorded a significant increase in all parameters of patients whose condition is critically compared with severe conditions, except Hs-CRP did not record significant differences; on the other hand, the study did not show significant differences in patients according to age groups. The current study showed a positive relationship between insulin and homo IR; between insulin and interleukin-10, the concentration of FBS and IL-10 increases with disease severity.
Keywords: Covid-19, Diabetic, IL-10, Hs-CRP, Insulin, Homo-IR.