Bee venom: A medical perspective

Researchers have been interested in honey bee, Apis mellifera L., venom for many years, but the previous studies focused mainly on its pharmacological properties and the factors aff ecting its production and chemical content were less well evaluated. This research aims to investigate the potential eff ect of the method of collecting bee venom on its chemical content. To achieve this, brass, steel, aluminium and copper wire conductors were used. This research was carried out at Van YYU Beekeeping Application and Research Centre, where the venom was collected dry on glass plates from 16 Caucasian F1 honey bee colonies. The quantity produced and its composition in terms of melittin, apamin and phospholipase A2 were determined after storage. Duncan and LSD Multiple Comparison tests on the amounts of venom collected using aluminium, copper, steel and brass wires for conducting electricity, revealed it was 21.03 ± 3.50, 15.08 ± 0.32, 22.38 ± 6.35 and 30.35 ± 3.66 mg, respectively. Although these values diff ered signifi cantly (p < 0.05), the chemical content of the bee venom was the same. The colour of the venom was associated with the material of the electrical conductor used. It was concluded that it would be benefi cial to carry out further studies using more colonies along with using residue analysis.* This article has been conducted from Nazım Turan's master thesis.

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Natural Sources of Therapeutic Agents Used in Skin Conditions

Dinu,

Tatu,

Cocoș

et al. 2024

Life

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Skin conditions are numerous and often have a major impact on patients’ quality of life, and effective and safe treatment is very important. The conventional drugs used for skin diseases are usually corticosteroids and antimicrobial products that can induce various side effects, especially with long-term use, which is why researchers are studying alternatives, especially biologically active natural products. Three products caught our attention: bee venom (BV), due to reported experimental results showing anti-inflammatory, antibacterial, antiviral, antioxidant, antimycotic, and anticancer effects, Ficus carica (FC) due to its demonstrated antioxidant, antibacterial, and anti-inflammatory action, and finally Geranium essential oil (GEO), with proven antifungal, antibacterial, anti-inflammatory, and antioxidant effects. Following a review of the literature, we produced this paper, which presents a review of the potential therapeutic applications of the three products in combating various skin conditions and for skin care, because BV, FC, and GEO have common pharmacological actions (anti-inflammatory, antibacterial, and antioxidant). We also focused on studying the safety of the topical use of BV, FC, and GEO, and new approaches to this. This paper presents the use of these natural therapeutic agents to treat patients with conditions such as vitiligo, melasma, and melanoma, as well as their use in treating dermatological conditions in patients with diabetes.

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Bee venom: A medical perspective

Cited by 5 publications

References 63 publications

Bee venom as a promising therapeutic strategy in central nervous system diseases

Bee venom as a promising therapeutic strategy in central nervous system diseases

The effect of conductor wires of different metals on the amount of honey bee (Apis mellifera; Hymenoptera: Apidae) venom collected and its chemical content

Natural Sources of Therapeutic Agents Used in Skin Conditions

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