Argon Laser Phototherapy in the Treatment of Refractory Fungal Keratitis

Pellegrino, Fernando; Carrasco, Marı́a Alejandra

doi:10.1097/ico.0b013e318256140e

Cited by 17 publications

(15 citation statements)

References 16 publications

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“…28 In 2013, Pellegrino and Carrasco reported excellent clinical outcomes after adjunctive laser application in 2 patients with refractory fungal keratitis. 25 …”

Section: Discussionmentioning

confidence: 99%

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Adjunctive Green Thermal Laser Photocoagulation for Treatment of Resistant Infectious Keratitis

Nasef¹,

El-Emam²,

Sharaf³

et al. 2021

OPTH

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Purpose To investigate the safety and efficacy of green thermal laser as an adjunctive therapy for the treatment of resistant infectious keratitis (IK) in the Delta region of Egypt. Methods A retrospective case series of 150 patients, within a 4 year duration, with resistant IK, who failed to respond to specific medical treatment alone for 7 days, were included. They all received green thermal laser photocoagulation treatment to the cornea as an adjunctive to medical treatment. Results Forty-eight women and 102 men were included in this study with a mean age of 46.2 ± 7.7 years. Common risk factors associated with IK included trauma by material of plant origin and contact lens wear. The mean duration of healing was 2.87 ± 0.7 weeks. A single session of green thermal laser application was adequate in 138 IK cases (92%), while 12 cases (8%) required an additional session a week later. Supplementary amniotic membrane transplantation (AMT) was required in 26 cases (17.3%). Two patients (1.3%) required tectonic keratoplasty for corneal perforation. The final corrected distance visual acuity (CDVA) was counting fingers (CF) or better in 78 patients (52%). No decrease of CDVA was reported throughout the study. Conclusion Green thermal laser is a safe and effective adjunctive therapy for the treatment of resistant infectious keratitis.

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“…28 In 2013, Pellegrino and Carrasco reported excellent clinical outcomes after adjunctive laser application in 2 patients with refractory fungal keratitis. 25 …”

Section: Discussionmentioning

confidence: 99%

“…24 A few recent studies have already documented the efficacy of green thermal laser as an adjunctive therapy for the management of resistant IK. 22 , 25 …”

Section: Introductionmentioning

confidence: 99%

Adjunctive Green Thermal Laser Photocoagulation for Treatment of Resistant Infectious Keratitis

Nasef¹,

El-Emam²,

Sharaf³

et al. 2021

OPTH

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“…Epithelial debridement is frequently used in the management of fungal keratitis to enhance the penetration of antifungals due to the large area of keratitis 14. Argon laser may have the same effect.…”

Section: Discussionmentioning

confidence: 99%

Role of argon laser as an adjunctive therapy for treatment of resistant infected corneal ulcers

Khater¹,

Selima²,

El-Shorbagy³

2014

OPTH

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PurposeTo evaluate the role of argon laser as an adjunctive therapy in ten patients with resistant infected corneal ulcers with or without hypopyon.MethodsThe study included 20 patients, split into two groups of ten, with resistant infected corneal ulcers with or without hypopyon. One group was considered as the control group and treated with local and systemic specific antimicrobial drugs guided with culture and sensitivity tests. The other group started with the same specific therapy as the control group for 1 week with no obvious improvement and then was further treated with argon laser. The ten patients in the control group included five cases of fungal ulcers, three mixed (fungal and bacterial) ulcers, and two viral ulcers. The ten patients in the other group included three cases of fungal ulcers, three mixed (fungal and viral) ulcers, three viral ulcers, and one bacterial ulcer as proven with microbial culture and sensitivity tests. Eight cases of the control group and seven cases of the other group were associated with hypopyon. Before laser treatment, a drop of benoxinate hydrochloride 0.4% and a single drop of fluorescein sodium 0.25% were instilled. Argon laser irradiation of the affected cornea was performed using an argon 532 nm wavelength (Carl Zeiss LSL 532s AG; Carl Zeiss Meditec AG, Jena, Germany). A spot size of 500 μm, pulse duration of 0.2 seconds, and power of 900 mW were used. All cases were followed up for 3 months after healing was achieved.ResultsDuring the first 4 weeks after laser treatment, all patients showed complete healing of the epithelial defect and resolution of stromal infiltration with no adverse effects. In the control group, four cases needed an amniotic membrane graft due to thinning and the other six cases were healed in a duration that ranged from 3 to 7 weeks.ConclusionArgon laser phototherapy is useful as an adjunctive treatment for resistant infected corneal ulcers. More cases are needed to get more reliable results and to confirm our findings.

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“…Es finden sich in der Literatur wenige Studien zur Behandlung von Hornhautulzera mittels Laser. Pellegrino et al berichten über 2 Patienten, bei denen es nach Argonlaserbehandlung einer therapierefraktären Fusarienkeratitis zur Abheilung kam [14]. In einer sehr kleinen Fall-Kontroll-Studie konnte nach Argonlaserbehandlung von Keratitiden eine schnellere Abheilung mit geringer Anzahl weiterer chirurgischer Maßnahmen und bei mehr Patienten ein Visusanstieg erzielt werden als in der Kontrollgruppe [15].…”

Section: Diskussionunclassified

In-vitro-Studie mit subablativem Er:YAG-Laser und Diodenlaser vs. Thermokauter zur Therapie der mikrobiellen Keratitis

Kampmeier

Werner

et al. 2018

Klin Monatsbl Augenheilkd

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Argon Laser Phototherapy in the Treatment of Refractory Fungal Keratitis

Abstract: Argon laser phototherapy is useful as an adjunctive treatment of refractory fungal keratitis. More cases are needed to validate our findings.

Cited by 17 publications

References 16 publications

Adjunctive Green Thermal Laser Photocoagulation for Treatment of Resistant Infectious Keratitis

Adjunctive Green Thermal Laser Photocoagulation for Treatment of Resistant Infectious Keratitis

Role of argon laser as an adjunctive therapy for treatment of resistant infected corneal ulcers

In-vitro-Studie mit subablativem Er:YAG-Laser und Diodenlaser vs. Thermokauter zur Therapie der mikrobiellen Keratitis

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