Are treatment guides and rational drug use policies adequately exploited in combating respiratory system diseases?

Abstract

The aim of the present study was to increase awareness regarding the rational use of medicines. The data were obtained via the Material Resources Management System Module of the Ministry of Health. For the appropriateness of treatments, the Global Initiative for Asthma, the Global Initiative for Chronic Obstructive Lung Disease, and the guidelines for the rational use of medicines were used. We also investigated whether any de-escalation method or physical exercise was performed. Statistical analyses were performed using descriptive statistics to determine the mean, standard deviation, and frequency. The results showed that healthcare providers ignored potential drug reactions or adverse interactions, and reflecting the lack of adherence to the current treatment guides, 35.8% irrational use of medicines was recorded. Thus, de-escalation methods should be used to decrease costs or narrow the antibiotic spectrum, antibiotic selection should consider the resistance patterns, culturing methods should be analyzed, and monotherapy should be preferred over combination treatments.

Evaluation of empirical antibiotic treatment in culture-negative pyogenic vertebral osteomyelitis

“…This causes an increase in bacterial resistance to the drugs. In addition, this may result in the prolongation of hospital stay and loss of labor, treatment failures, adverse drug reactions, side effects, increased treatment costs, and mortality (2,3,10,20).…”

“…The World Health Organization emphasizes that patients should use the medications that are appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period, and at the lowest cost to them and their community (10,16,20). The application of drugs, also called "rational antibiotic use", necessitates the development of appropriate antibiotic usage policies.…”

Evaluation of Antibiotic Alternatives Used in Orthopedic Departments of 2 Hospitals According to Rational Use of Antibiotics

“…[14][15][16] There have been reports from many European countries, including Turkey, of adverse outcomes concerning inappropriate antibiotic use and widespread antibiotic resistance. [17] In a study where European countries were compared, it was emphasized that in France inappropriate use of antibiotics was a great public health problem, and antibiotics costs should be urgently reduced. [18][19][20] In a study published by the World Health Organization (WHO) Regional Office for Europe, it was reported that in many countries, including Turkey, broad spectrum antibiotics were being used with increasing frequency, and that excessive use of thirdgeneration cephalosporins was indicated in Turkey.…”

Consumer Awareness, Attitude, and Behavior Related to the Rational Use of Medicines in a Developing Country Context: The Case of Turkey

“…It is also stated that more comprehensive policies are needed for RUM [21]. In recent years, studies on rational drug use have been carried out in specific groups such as hypertensive, diabetic, and neonates [22], [23], [24]. The adoption and recognition of policies for practitioners and consumers are highly effective on success.…”