Are Thyroid Functions Effective in Pregnant Women with Hyperemesis Gravidarum?

Güler, Aşkın Evren; Yıldız, Birol; Çakmak, Bülent; Güler, Zeliha Çiğdem Demirel; Kıncı, Mehmet Ferdi

doi:10.5152/cjm.2019.19008

Cited by 2 publications

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“…Subclinical hypothyroidism has been associated with adverse effects such as preeclampsia, placental abruption, postpartum hemorrhage, cardiac dysfunction, low birth weight and intrauterine fetal death (7). On the other hand, hyperthyroidism has been associated with preeclampsia, heart failure, preterm delivery, intrauterine growth retardation, thyrotoxicosis and hyperemesis gravidarum (7,8).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Thyroid Functions in Adolescent, Normal and Advanced Age Pregnancies

Kıncı

Paskal

Saruhan

et al. 2021

Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi

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ÖzWe aimed to investigate the thyroid function test (fT4 and TSH) results and the prevalence of hyperthyroidism, euthyroidism, subclinical hypothyroidism, and overt hypothyroidism according to age groups in pregnant women who had applied to our hospital. Six thousand eight hundred and fourty-three pregnant women who were in the first trimester and who applied to the hospital for the first time in their current pregnancy were included in the study. Patients were divided into 3 age groups, namely, ≤19 years, 20-34 years, and ≥35 years. The fT4 and TSH levels were compared between the age groups. The mean serum TSH value of patients was 1.61(0.987, 2.41) mIU/mL. There was no statistically significant difference in the rates of hyperthyroidism, euthyroidism, subclinical hypothyroidism and overt hypothyroidism between the three age groups. However, the incidence of hyperthyroidism in pregnant women aged 35 years and older was significantly higher when compared with those aged 35 years and younger. Consistently with the previous studies in our country, the prevalence of hyperthyroidism, subclinical hypothyroidism and overt hypothyroidism was detected as 2.9%, 22.1%, and 0.4%, respectively. Therefore, we recommend regular thyroid testing in pregnancy regardless of age, especially in countries where iodine deficiency is common.Bu çalışmada, hastanemize başvuran gebe kadınların tiroid fonksiyon testi (fT4 veTSH) sonuçlarını ve bu sonuçlara göre hipertiroidi, ötiroidi, subklinik hipotiroidi ve aşikar hipotiroidi sıklığını yaş gruplarına göre değerlendirdik. Mevcut gebeliğinde ilk defa hastaneye başvuran birinci trimestrde olan 6843 gebe çalışmaya dahil edildi. Hastalar 19 yaş altı, 20-34 yaş arası ve 35 yaş üzeri şeklinde 3 gruba ayrıldı. fT4 ve TSH değerleri gruplar arasında karşılaştırıldı. Gebelerin ortalama TSH değerleri 1.61 (0.987, 2.41) mIU/mL'idi. Çalışma grupları arasında hipertiroidi, ötiroidi, subklinik hipotiroidi ve aşikar hipotiroidi açısından istatistiksel olarak anlamlı fark izlenmedi. Fakat, 35 yaş üzerindeki gebelerde hipertiroidi sıklığı 35 yaş altındaki gebelere göre daha fazla izlendi. Ülkemizdeki diğer çalışmalara benzer şekilde sırası ile; hipertiroidi, subklinik hipotiroidi ve aşikar hipotiroidi sıklığı %2.9, %22.1 ve %0.4 olarak saptanmıştır. Bu nedenle, özellikle ülkemiz gibi iyot eksikliği sık olan bölgelerde yaş ayrımı gözetmeksizin gebelerde tiroid fonksiyonlarının çalışılmasını öneriyoruz.

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Section: Introductionmentioning

confidence: 99%

Evaluation of the Thyroid Functions in Adolescent, Normal and Advanced Age Pregnancies

Kıncı

Paskal

Saruhan

et al. 2021

Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi

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“…Hyperthyroidism during pregnancy is a much rare condition as compared to hypothyroidism with a prevalence of about 0.2% (5). An untreated hyperthyroidism during pregnancy has been associated with perinatal complications such as Medical Science and Discovery, 2020; 7(2):419-24 preeclampsia, preterm labor, fetal loss and hyperemesis gravidarum (6,7).…”

Section: Introductionmentioning

confidence: 99%

Hypothyroidism prevalence in pregnant women according to age groups

Çoşkun

Kinci

et al. 2020

Med Sci Discov

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Objective: Investigation of the thyroid function test (fT3, fT4 and TSH) results and the prevalence of overt/subclinical hypothyroidism according to age groups in patients who had applied to our hospital and diagnosed with pregnancy. Material and Methods: Two thousand nine hundred and thirty-six women diagnosed with pregnancy for the first time upon seeing the fetal heartbeats with ultrasonography between January 2015 and December 2018, were included in our study. Patients were divided into 5 age groups, namely, the age groups of ≤18 years of age, 19-25 years, 26-35 years, 36-45 years and >45 years of age. The fT3, fT4 and TSH levels were statistically compared between all the patients and age groups. Results: Two thousand nine hundred and thirty-six pregnant women were included in the study. The mean fT3 value was found as 3.180±0.519 (pg/mL), fT4 value as 1.051±0.258 (ng/d/L) and TSH value was found as 2.000±1.595 (mIU/mL) in all the population. The mean fT3, fT4 and TSH values were not statically different among the age groups (p=0.06, p=0.08 and p=0.829, respectively). No statistically significant differences were found among all the age groups as regards hyperthyroidism, euthyroidism, subclinical hypothyroidism and overt hypothyroidism (p=0.200). Conclusion: Consistently with the previous studies in our country, the prevalence of subclinical hypothyroidism was found as high as 22.7% in our study. We think that scanning for hypothyroidism must be performed in the pregnancy period without discriminating between risk groups in our country, which is located in the iodine deficiency region. However, considering the different age groups, we believe that TSH levels must be measured with the same apprehensiveness for each age group since no statistically significant differences are found between age groups.

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Are Thyroid Functions Effective in Pregnant Women with Hyperemesis Gravidarum?

Cited by 2 publications

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Evaluation of the Thyroid Functions in Adolescent, Normal and Advanced Age Pregnancies

Evaluation of the Thyroid Functions in Adolescent, Normal and Advanced Age Pregnancies

Hypothyroidism prevalence in pregnant women according to age groups

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