Are There Any Sensitive and Specific Sex Steroid Markers for Polycystic Ovary Syndrome?

Abstract

Although it is commonly believed that recovery from subtotal abdominal hysterectomy (SH) is associated with fewer complications and less pelvic organ dysfunction than total abdominal hysterectomy (TH), there is little data supporting this belief in the literature. Previous studies have found no difference in the postoperative recovery time between these procedures. Overall recovery after hysterectomy depends on treatment of postoperative physical symptoms and complications. Some studies have shown that recovery also depends on preoperative psychological well being and postoperative overall well being. The impact of these factors on the postoperative day-by-day recovery has not been investigated.This prospective randomized, controlled, open, multicenter study assessed possible differences between SH and TH in the day-by-day postoperative recovery, and also analyzed factors associated with postoperative recovery and sick leave. The study was conducted at 7 hospitals and 1 private gynecological clinic in Sweden between 1998 and 2004. The study subjects were 200 women who were scheduled for hysterectomy because of benign gynecological conditions. Of the 178 patients who completed the study, 94 were randomized to a SH group and 84 to a TH group. Assessment of day-by-day recovery of general well being was made using a patient diary with daily entries initiated at 1 week before surgery and continuing until the 35th postoperative day; the results were calculated on a visual analogue scale. Psychometric measurements included depression and anxiety; general psychological well being was also assessed. The primary study outcome measures were the associations between day-by-day recovery of general well being and duration of sick leave with mode of hysterectomy.The data showed no significant difference in the SH and TH groups for the day-by-day recovery of general well being in the preoperative and postoperative periods. A strong association was found between both postoperative day-by-day recovery of general well being and the duration of sick leave, with the occurrence of minor complications, but there was no significant association for major complications. The postoperative day-by-day recovery of general well being and duration of sick leave were strongly associated with the level of preoperative psychological well being.These findings show no difference in the speed of day-by-day recovery of general well being between the 2 procedures, but demonstrate an association between postoperative recovery of general well being and the duration of sick leave with preoperative psychological well being. Strong determinants for a prolonged sick leave include minor postoperative complications and a low preoperative level of psychological well being. GYNECOLOGY Volume 65, Number 6 OBSTETRICAL AND GYNECOLOGICAL SURVEY ABSTRACTPrevious studies have shown that the new minimally invasive mid-urethral tape procedures are as effective or even more effective in curing female stress urinary incontinence (SUI) than the traditional methods. An esse...

Longitudinal Study of Insulin Resistance and Sex Hormones over the Menstrual Cycle: The BioCycle Study

“…However, it follows the evidence that women with insulin resistance as seen in PCOS have lower FSH levels (39).…”

Dietary intake, resting energy expenditure, and eating behavior in women with and without polycystic ovary syndrome

“…Participants were recruited by advertising in local newspapers and in frequently visited places in the community and have been described in detail elsewhere [19,20]. Potential participants for the study were asked to describe their medical histories and underwent a gynecological examination and a two-dimensional transvaginal ultrasonography (HDI 5000, ATL, Bothell, Washington) to determine ovarian morphology.…”

Uterine Morphology and Peristalsis in Women with Polycystic Ovary Syndrome

“…Estrogens have been observed to stimulate uterine peristalsis (11,12). Based on previous observations that circulating estradiol levels are higher in women with PCOS than in controls (13), one may speculate that the endometrium is thicker, and that peristalsis is increased in PCOS compared to controls. If so, it would also be of interest to investigate if a potential difference in the thickness of the uterine wall or JZ under hormonal influence could be an explanatory factor for differences in detection of peristalsis.…”