Are the site, diameter, and number of endometrial polyps related with symptomatology?

Hassa, Hikmet; Tekin, Başar; Senses, Tanser; Kaya, Muammer; Karataş, Ahmet

doi:10.1016/j.ajog.2005.08.060

Cited by 46 publications

(23 citation statements)

References 15 publications

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“…Some authors such as Savelli et al [5] and Giordano et al [26] found a correlation between hormone replacement therapy, obesity and malignancy, whereas Antunes et al [27] did not. Ben-Arie et al [9] found importance in the size of the polyp, but Hassa et al [25] did not.…”

Section: Discussionmentioning

confidence: 99%

“…However, due to the small sizes of the groups receiving these medications and the absence of information about the median duration of treatment or the type of HRT, one must be careful in making premature conclusions. The controversy related to the correlation between exposure to the tamoxifen and HRT treatment and malignancy is well documented [1,5,[23][24][25][26][27] . In our study, we present no data relating to polyp size, number and the connection to symptomatology and malignancy.…”

Section: Discussionmentioning

confidence: 99%

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Endometrial Polyps: Symptomatology, Menopausal Status and Malignancy

Golan¹,

Cohen-Sahar²,

Keidar³

et al. 2010

Gynecol Obstet Invest

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Aims: To assess the frequency of premalignant and malignant endometrial polyps in symptomatic and asymptomatic women. Methods: Retrospective registration of 1,124 patients who underwent hysteroscopic resection of endometrial polyps. Patient characteristics included age, menopausal status, presence or absence of symptoms, and use of hormonal medication. Histological diagnoses and complications were also analyzed. Results: 641 (57%) of 1,124 women with endometrial polyps were postmenopausal and 483 (43%) premenopausal. Abnormal uterine bleeding was reported by 548 women: 226 (49%) postmenopausal and 322 (51%) premenopausal. 576 (51%) women were asymptomatic. There were 16 patients with malignancy or premalignant conditions among the symptomatic patients (2.7%) compared to 7 such patients among the asymptomatic patients (1.3%; p = 0.17). Pathologic evaluation disclosed 7 cases of malignancy and 4 cases of atypical hyperplasia among bleeding postmenopausal women (11/263, 4%) and 2 malignancies and 3 cases of hyperplasia with atypia among asymptomatic postmenopausal women (5/378, 1.3%). Conclusion: We found premalignancy and malignancy in each patient group – pre- and postmenopausal, as well as symptomatic and asymptomatic. We recommend removal of any verified endometrial polyp.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Endometrial Polyps: Symptomatology, Menopausal Status and Malignancy

Golan¹,

Cohen-Sahar²,

Keidar³

et al. 2010

Gynecol Obstet Invest

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“…8 ). There is no relation between symptoms and the size or number of polyps 9 . The presence of polyps also may not be the cause of uterine bleeding.…”

Section: Discussionmentioning

confidence: 99%

Comparison of ultrasound with hysteroscopic and histological findings for intrauterine assessment

Reznak¹,

Kudela²

2018

BIOMED PAP

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Introduction. Hysteroscopy with biopsy is a common diagnostic and therapeutic method in gynaecology. Its use is preceded by ultrasound examination. The success rate of predicting intrauterine findings based on ultrasound has not been assessed in the Czech Republic for a long time. In the meantime, there have been technological improvements in ultrasound devices. Method. Patients indicated for hysteroscopy underwent ultrasound examination and their medical history was recorded. The percentage agreement between ultrasound and histopathological findings was assessed. The secondary goal was to find an easier way of describing ultrasound findings in gynaecological practice. Results. The study comprised 255 patients. In 15 cases, endometrial carcinoma was confirmed by hysteroscopy and histopathological examination. Of these, malignancies were suspected based on previous ultrasound scans in 11 patients. In 95 cases, intrauterine polyps were detected. The success rate for predicting polyps by ultrasound examination was 65.1%. The agreement between ultrasound and hysteroscopic/histopathological findings was 72%. The secondary goal of making the description of the uterine cavity easier was not fulfilled. The prediction percentages for the criteria were low. The incidence of pathological findings in ultrasound findings labelled as anechogenic was 4.8%, suggesting a high negative predictive value. Conclusion. In spite of the better resolution of new ultrasound devices, their predictive value remains limited. Findings that are suspicious in ultrasound should be confirmed by hysteroscopy with biopsy.

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“…Although endometrial polyps are responsible for approximately one-fourth of cases of abnormal genital bleeding (menorrhagia, postmenopausal bleeding, prolapse through the cervical os, and breakthrough bleeding during hormonal therapy) in both premenopausal and postmenopausal women [ 1 ], many polyps are asymptomatic [ 13 ].…”

Section: Introductionmentioning

confidence: 99%