2010
DOI: 10.4103/0028-3886.68669
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Are somatosensory evoked potentials of the tibial nerve the most sensitive test in diagnosing multiple sclerosis?

Abstract: Tibial SEPs produce the most abnormal results and the highest sensitivity in the RR-MS. We propose that this test as useful criterion for the diagnosis of MS.

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Cited by 11 publications
(12 citation statements)
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“…Yaldizli et al were able to explain 56% of EDSS variance after mean of 7.1 years by using EDSS at diagnosis along with other clinical and MRI variables, while Deloire et al explained 56 and 71% of EDSS change at 5 and 7 years, respectively, using EDSS at baseline and age along with either Symbol Digit Modalities Test or consistent long-term retrieval [16,17]. Due to major differences in patients' characteristics, methods and regressor variables, none of the preceding works are directly comparable with ours; noteworthy, neurophysiological variables have been never included as regressors in spite of being still widely used to diagnose and monitor the disease [18,19]. Nonetheless, a generalized difficulty in accurate long-term prediction of disability with multivariate models seems to emerge.…”
Section: Discussionmentioning
confidence: 49%
“…Yaldizli et al were able to explain 56% of EDSS variance after mean of 7.1 years by using EDSS at diagnosis along with other clinical and MRI variables, while Deloire et al explained 56 and 71% of EDSS change at 5 and 7 years, respectively, using EDSS at baseline and age along with either Symbol Digit Modalities Test or consistent long-term retrieval [16,17]. Due to major differences in patients' characteristics, methods and regressor variables, none of the preceding works are directly comparable with ours; noteworthy, neurophysiological variables have been never included as regressors in spite of being still widely used to diagnose and monitor the disease [18,19]. Nonetheless, a generalized difficulty in accurate long-term prediction of disability with multivariate models seems to emerge.…”
Section: Discussionmentioning
confidence: 49%
“…La mayor alteración fue encontrada en PESS de nervio tibial posterior y mediano y resultados similares a los nuestros se encontraron para el PEV y el PEATC. 19 Con respecto a la naturaleza de las lesiones, los resultados de los estudios electrofisiológicos de los pacientes incluidos en este trabajo se correspondieron con lo reportado por otros autores, [20][21][22] encontrando que la mayor parte de las alteraciones estuvieron referidas a las variables que denotan la existencia de un daño desmielinizante (latencia absoluta, intervalos interpicos, distorsión morfológica y ausencia de componentes). Nuevamente se registró el mayor porcentaje de anomalías en los potenciales que exploran las vías más largas (somestésica y visual) que se manifiestan fundamentalmente por la afectación de latencia y distorsión morfológica, referido a la afectación de la mielina, característica preponderante de esta enfermedad.…”
Section: Discusión De Los Resultadosunclassified
“…The diagnostic value of SSEP is most pronounced in diagnostic evaluation of patients with no evidence of demyelinating lesions on the spinal MRI. Tibial SSEP is considered to be among the most valuable EPs (14), giving pathological findings in up to 80% of patients with MS who do not have sensory symptoms and signs (15).…”
Section: Evoked Potentials In Multiple Sclerosismentioning
confidence: 99%