Are pregnancy, parity, menstruation and breastfeeding risk factors for thyroid cancer? Results from the Korea National Health and Nutrition Examination Survey, 2010‐2015

Kim, Hosu; Kim, Kyong Young; Baek, Jong Ha; Jung, Jaehoon

doi:10.1111/cen.13750

Cited by 7 publications

(6 citation statements)

References 21 publications

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“…In support of our results, two previous studies performed in Japan and Thailand found that thyroid cancer risk was decreased among women who had experienced pregnancy compared with those who had not [28,29]. However, many previous studies suggested that the number of pregnancies and parity could increase the risk for thyroid cancer [6,12,[30][31][32]. Additionally, some studies have suggested no significant association between the number of pregnancies and the risk of thyroid cancer [4,10,11].…”

Section: Discussionsupporting

confidence: 88%

Analysis of the Association between Female Medical History and Thyroid Cancer in Women: A Cross-Sectional Study Using KoGES HEXA Data

Jin

Lee

Song

et al. 2021

IJERPH

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The purpose of this study was to evaluate the association between female medical history and thyroid cancer. Methods: Data from the Korean Genome and Epidemiology Study were collected from 2004 to 2016. Among a total of 1303 participants with thyroid cancer and 106,602 control (non-thyroid cancer) participants, the odds ratios (ORs) with 95% confidence intervals (CIs) of hysterectomy, oophorectomy, use of oral contraceptives, and number of children were evaluated. Results: The adjusted OR of hysterectomy for thyroid cancer was 1.73 (95% CI = 1.48–2.01, p < 0.001) in the minimally adjusted model. The adjusted ORs for thyroid cancer were 1.89 (95% CI = 1.06–3.37, p = 0.031), 0.89 (95% CI = 0.83–0.94, p < 0.001), and 0.85 (95% CI = 0.73–0.99, p = 0.040) for bilateral oophorectomy, number of children, and use of oral contraceptives, respectively, in the fully adjusted model. In the subgroup analysis, the adjusted ORs of bilateral oophorectomy were significant in the younger age (OR = 3.62, 95% CI = 1.45–9.03, p = 0.006), while the number of children was significant in the older age (OR = 0.86, 95% CI = 0.80–0.93, p < 0.001). Conclusions: The ORs of hysterectomy and bilateral oophorectomy were significantly higher in the thyroid cancer group in the younger age group. The adjusted ORs of the number of children were significantly low in the older age group.

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Section: Discussionsupporting

confidence: 88%

Analysis of the Association between Female Medical History and Thyroid Cancer in Women: A Cross-Sectional Study Using KoGES HEXA Data

Jin

Lee

Song

et al. 2021

IJERPH

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“…This is similar to the results of a non-Korean study in which it was verified that longer breastfeeding duration was associated with a lower prevalence of thyroid cancer [15]. The study of some female thyroid cancer patients in Korea also reported that breastfeeding period and the number of breastfeeding babies were associated with the risk of thyroid cancer [18]. A dose-response relationship between the total breastfeeding duration and the prevalence of thyroid cancer has thus been potentially confirmed in Korean women as well.…”

Section: Lower Prevalence Of Thyroid Cancer In the Longer Breastfeeding Duration Groupsupporting

confidence: 88%

“…In the case of Korean women, a trend emerged where decreasing breast cancer risk was associated with an increased duration of breastfeeding [16,17], while the total duration of breastfeeding significantly decreased the risk of thyroid cancer [18]. However, it is hard to find a study that confirms the link between breastfeeding and cervical cancer.…”

Section: Introductionmentioning

confidence: 99%

Association between breastfeeding and breast, thyroid, and cervical cancer among Korean adult women: based on the Korean Genome and Epidemiology Study

Jin

Kang

Son

2021

Korean J Women Health Nurs

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Purpose: The purpose of this study was to explore the relationship between breastfeeding and the prevalence of breast, thyroid, and cervical cancer among Korean adult women.Methods: The study was a secondary analysis of data from the Korea Genome and Epidemiology Study. The final samples were 113,944 Korean women among 173,205 urban-based cohort participants collected between 2004 and 2013 for adults aged forty and over. To determine the association between female cancers and breastfeeding experience, the number of childbirth, and total breastfeeding duration, logistic regression analysis was done. The demographic characteristics, health behavior, and female history were adjusted.Results: The prevalence of breast cancer was 1.37 times higher in non-breastfeeding group than in breastfeeding group. Compared to having breastfed for more than 36 months, the prevalence of thyroid cancer was 1.68 times higher at breastfeeding for 13 to 36 months, 1.67 times higher at breastfeeding for 6 to 12 months, and 2.06 times higher at breastfeeding less than 6 months. Also, the prevalence of cervical cancer was 1.54 times higher at breastfeeding for 13 to 36 months compared to breastfeeding for more than 36 months.Conclusion: The study provides that breastfeeding experience and the longer breastfeeding duration have reduced the risk of breast, thyroid, and cervical cancer in Korean women. It can be used as a basis for encouraging breastfeeding, which is identified to reduce the risk of breast, thyroid, and cervical cancers in Korean women.

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“…Similarly, Dong Zhang found that the association between arti cial light at night and risk for TC was primarily driven by PTC and was more potent in women (HR, 1.81; 95% CI, 1.26-2.60) than men (HR, 1.29; 95% CI, 0.86-1.94) 6 . There is a gender difference because the occurrence of TC is closely related to estrogen 37 . Research has suggested that estrogen receptor polymorphism in TC contributed to the difference in TC incidence between men and women 11,12 .…”

Section: Discussionmentioning

confidence: 99%

Rotating shift work Is Associated with increased risk of thyroid carcinoma ： an ecological study of 178905 workers in 35 European countries between 2000 and 2015

Yang,

Yan,

Han

et al. 2023

Preprint

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Objective:Previous studies have shown that circadian disruption can affect thyroid hormone levels, but whether it elevates the risk of thyroid cancer (TC) is still controversial. The present study investigates the relationship between rotating shift work (RSW) and the incidence of TC. Methods:The prevalence of RSW in the 35 European countries from 2000 to 2015 was estimated based on the data of 89257 men and 81749 women of the European Working Condition Survey. The incidence of TC was obtained from the Global Burden of Disease database. We analyzed the relationship between the prevalence of RSW and the incidence of TC 5 years later (TC5). We used a mixed model with adjustment of country-specific GDP per capita, Volcanic region, age, Education attainment rate, obesity rate and occupational radiation exposure rate. Results: The prevalence of RSW was significantly associated with the incidence of TC5 (β = 0.03 95%CI:0.01, 0.06, P=0.03). For a quartile increase in RSW, the incidence of TC5 increased by 0.18 per 100000（95%CI：0.05 per 100000,0.33 per 100000）. When separately analyzed in the two genders, we found an association between the two in women (β = 0.04, 95%CI: 0.01, 0.08, P=0.02), but not in men (β = 0.01, 95% CI: -0.03, 0.04, P=0.75). Conclusion: Circadian disruption may be associated with an increase in the overall risk of TC, but it only seems to affect the occurrence of TC in women, not men. Further research is needed to verify the findings of the present study.

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Are pregnancy, parity, menstruation and breastfeeding risk factors for thyroid cancer? Results from the Korea National Health and Nutrition Examination Survey, 2010‐2015

Abstract: Our findings suggest that reproductive factors can be associated with the development of thyroid cancer. A large prospective cohort study is needed to clarify the causality.

Cited by 7 publications

References 21 publications

Analysis of the Association between Female Medical History and Thyroid Cancer in Women: A Cross-Sectional Study Using KoGES HEXA Data

Analysis of the Association between Female Medical History and Thyroid Cancer in Women: A Cross-Sectional Study Using KoGES HEXA Data

Association between breastfeeding and breast, thyroid, and cervical cancer among Korean adult women: based on the Korean Genome and Epidemiology Study

Rotating shift work Is Associated with increased risk of thyroid carcinoma ： an ecological study of 178905 workers in 35 European countries between 2000 and 2015

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