Are Outcomes of Extremely Preterm Infants Improving? Impact of Bayley Assessment on Outcomes

Vohr, Betty R.; Stephens, Bonnie E.; Higgins, Rosemary D.; Bann, Carla; Hintz, Susan R.; Das, Abhik; Newman, Jamie; Peralta‐Carcelen, Myriam; Yolton, Kimberly; Dusick, Anna M.; Evans, Patricia W.; Goldstein, Ricki F.; Ehrenkranz, Richard A.; Pappas, Athina; Adams‐Chapman, Ira; Wilson-Costello, Deanne E.; Bauer, Charles R.; Bodnar, Anna; Heyne, Roy J.; Vaucher, Yvonne E.; Dillard, Robert G.; Acarregui, Michael J.; McGowan, Elisabeth C.; Myers, Gary J.; Fuller, Janell

doi:10.1016/j.jpeds.2012.01.057

Cited by 221 publications

(183 citation statements)

References 21 publications

Supporting

Mentioning

168

Contrasting

Unclassified

Order By: Relevance

“…[16][17][18][19][20][21] Given growing concern regarding constitution of the Bayley-III standardization sample and the underestimation of developmental delay, a cut-off score of 80 is recommended for defining moderate to severe developmental delay when using Bayley-III composite scores. [21] We therefore defined developmental delay for this study as follows: Bayley-III cognitive composite score <80 as cognitive delay; Bayley-III language composite score <80 as language delay; and a cognitive or language composite score <80 as any developmental delay.…”

Section: Methods Participantsmentioning

confidence: 99%

Correcting for prematurity affects developmental test scores in infants born late and moderately preterm

Parekh

Boyle

Guy

et al. 2016

Early Human Development

View full text Add to dashboard Cite

show abstract

Section: Methods Participantsmentioning

confidence: 99%

Correcting for prematurity affects developmental test scores in infants born late and moderately preterm

Parekh

Boyle

Guy

et al. 2016

Early Human Development

View full text Add to dashboard Cite

show abstract

“…7,13 The BSID-III is a standardized test for children 1 to 42 months that includes scaled and composite scores, percentile ranks, and age equivalents (with confidence intervals [CIs]) for cognitive, language, and motor scores. Composite scores have a mean of 100 and an SD of 15.…”

Section: Methodsmentioning

confidence: 99%

“…1,2 ELBW infants have high rates of adverse cognitive and language outcomes that persist through school age. [3][4][5][6][7] Infants of adolescent mothers also have adverse developmental outcomes on a variety of measures. [8][9][10] There is limited research on the combined risk of extreme prematurity and having an adolescent mother.…”

Section: What This Study Addsmentioning

confidence: 99%

Developmental Outcomes of Extremely Preterm Infants Born to Adolescent Mothers

et al. 2015

View full text Add to dashboard Cite

BACKGROUND AND OBJECTIVES: Extremely preterm infants and infants born to adolescent mothers are at risk for adverse developmental. The objectives were to evaluate development and behavior outcomes of extremely low birth weight (ELBW) infants born to adolescent mothers ,20 compared with adult mothers $20 years and to identify socioeconomic risk factors that affect outcomes.METHODS: Retrospective cohort analysis of 211 infants .27 weeks of adolescent mothers and 1723 infants of adult mothers at Neonatal Research Network centers from 2008 to 2011. Groups were compared and regression models were run to predict 18-to 22-month adverse outcomes. Primary outcomes were Bayley-III scores, neurodevelopmental impairment, and Brief Infant Toddler Social Emotional Assessment problem scores (BITSEA/P) $75th percentile.RESULTS: Adolescent mothers were more often single, Hispanic, less educated, and had public insurance. By 18 to 22 months, their children had significantly increased rates of having lived $3 places (21% vs 9%), state supervision (7% vs 3%), rehospitalization (56% vs 46%), and BITSEA/ P $75th percentile (50% vs 32%) and nonsignificant Bayley-III language scores ,85 (56% vs 49%, P = .07). In regression analysis, children of adolescent mothers were more likely to have BITSEA/P $75th percentile (relative risk 1.50, 95% confidence interval 1.08-2.07). Living $3 places and nonwhite race were predictors of adverse behavior. State supervision was an independent predictor of each Bayley-III composite ,70 and neurodevelopmental impairment.CONCLUSIONS: ELBW infants of adolescent mothers experience high social and environmental risks that are associated with adverse behavior outcomes. These findings inform the need for comprehensive follow-up, coordinated care services, and behavior interventions for ELBW infants of adolescent mothers.WHAT'S KNOWN ON THIS SUBJECT: Infants born extremely premature and infants born to adolescent mothers are at risk for adverse developmental and behavior outcomes. There is limited research on the dual risk imparted to infants born extremely premature to adolescent mothers. WHAT THIS STUDY ADDS:Extremely premature infants of adolescent mothers have significantly increased rates of behavior problems. Nonwhite race and living in $3 places by 18 to 22 months of age are risk factors for adverse behavior outcomes among infants of adolescent mothers. Dr Hoffman conceptualized and designed the study, drafted the initial manuscript, and approved the final manuscript as submitted; Dr Bann performed all the statistical analysis; Dr Higgins reviewed and approved the research protocol and final manuscript; and Dr Vohr mentored and assisted Dr Hoffman in conceptualizing and designing the study, revising the manuscript, and approving of the final manuscript as submitted. There are multiple coexisting socioeconomic and biologic factors that place extremely preterm infants of adolescent mothers at increased risk for adverse developmental and behavioral outcomes. Previous studies of extremely preterm in...

show abstract

“…CB-III scores ,80 have been recommended for classifying moderate/severe developmental delay 19 to account for the well-documented underestimation of delay produced by using a conventional cutoff of Bayley-III scores ,70. [20][21][22] Three children for whom Bayley-III assessments could not be completed because of severe developmental problems were assigned the lowest Bayley-III scores for each scale (cognitive = 55; language = 47). To enable comparison with previous validation studies, predicted Bayley Scales of Infant Development-II Mental Development Index (predicted-MDI) scores were derived from Bayley-III scores by using a published algorithm.…”

Section: Methodsmentioning

confidence: 99%

A Parent Questionnaire for Developmental Screening in Infants Born Late and Moderately Preterm

et al. 2014

View full text Add to dashboard Cite

BACKGROUND: The Parent Report of Children’s Abilities-Revised (PARCA-R) is a questionnaire for assessing cognitive and language development in very preterm infants. Given the increased risk of developmental delay in infants born late and moderately preterm (LMPT; 32–36 weeks), this study aimed to validate this questionnaire as a screening tool in this population. METHODS: Parents of 219 children born LMPT completed the PARCA-R questionnaire and the Brief Infant Toddler Social and Emotional Assessment when children were 24 months corrected age (range, 24 months–27 months). The children were subsequently assessed by using the cognitive and language scales of the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III). RESULTS: An average Bayley-III, cognitive and language (CB-III) score and a total PARCA-R Parent Report Composite (PRC) score were computed. There was a large association between PRC and CB-III scores (r = 0.66, P < .001) indicating good concurrent validity. Using Youden index, the optimum PARCA-R cutoff for identifying children with moderate/severe developmental delay (CB-III scores < 80) was PRC scores < 73. This gave sensitivity 0.90 (95% confidence interval: 0.75–1.00) and specificity 0.76 (95% confidence interval: 0.70–0.82), indicating good diagnostic utility. Approximately two-thirds of the children who had a PRC score < 73 had false-positive screens. However, these children had significantly poorer cognitive and behavioral outcomes than children with true negative screens. CONCLUSIONS: The PARCA-R has good concurrent validity with a gold standard developmental test and can be used to identify LMPT infants who may benefit from a clinical assessment. The PARCA-R has potential for clinical use as a first-line cognitive screening tool for this sizeable population of infants in whom follow-up may be beneficial.

show abstract

Are Outcomes of Extremely Preterm Infants Improving? Impact of Bayley Assessment on Outcomes

Cited by 221 publications

References 21 publications

Correcting for prematurity affects developmental test scores in infants born late and moderately preterm

Correcting for prematurity affects developmental test scores in infants born late and moderately preterm

Developmental Outcomes of Extremely Preterm Infants Born to Adolescent Mothers

A Parent Questionnaire for Developmental Screening in Infants Born Late and Moderately Preterm

Contact Info

Product

Resources

About