Are increased left ventricular strains compensatory effects in lipedema? Detailed analysis from the three‐dimensional speckle‐tracking echocardiographic MAGYAR‐Path Study

Abstract

Purpose Lipedema is a chronic, common but underdiagnosed disease masquerading obesity, with female predominance, characterized by disproportional abnormal adipose tissue distribution of the lower and also upper extremities. The present study was designed to determine whether lipedema is associated with three‐dimensional (3D) speckle‐tracking echocardiography (3DSTE)‐derived left ventricular (LV) deformation abnormalities, and to assess the effects of 1‐hour use of medical compression stockings (MCS). Methods The present study comprised 19 female patients with lipedema (mean age: 42.2 ± 12.4 years), compared to 28 age‐matched healthy female controls (mean age: 42.0 ± 9.8 years). Results Lipedema patients showed larger left atrial and LV dimensions and greater LV ejection fraction than controls, without significant difference in other echocardiography variables. Lipedema patients had greater 3DSTE‐derived global and mean segmental LV circumferential and area strains than controls. Following 1‐hour use of wearing MCS, neither global and nor mean segmental LV strains showed significant impairment or improvement. Conclusions Increased LV strains could be compensatory effects maintaining LV pumping function in lipedema. Short‐term wearing of MCS has no global effect on LV strains.

Lipoedema as a Social Problem. A Scoping Review

“…The diameter of the left ventricle in the control group was 45.8 ± 3.2 mm, and in the study group it was 49.8 ± 3.2 mm. The ejection fraction in the control group was 64.3 ± 4.3%, and in the study group it was 68.3 ± 3.6% [ 31 ].…”

“…The research was conducted using PRISMA methodotogy (Figure 1) The review was conducted according to the PRISMA method and it distinguished 10 papers, which are presented in Table 1. Qualitative research • Subjective self-evaluation of the impact of lipoedema on health [28] Case study • Lipoedema and eating disorders [29] Pilot study • The connection between pain and psychological stress in people with lipoedema [20] Other study • Lipoedema comorbidities [30] • Left atrial and ventricular abnormalities in people with lipoedema [31] 3. Results…”

Left Ventricular Rotational Abnormalities in Treated Hypopituitarism: Insights From the Three-Dimensional Speckle-Tracking Echocardiographic MAGYAR-Path Study

“…Early detection of changes in LV volumetric and functional abnormalities could help in selecting patients with increased risk. In recent studies, diagnostic and prognostic impact of LV deformation have been demonstrated in several disorders (12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22). LV has a special 3D movement respecting the cardiac cycle as well due to its special helical 3D structure.…”

Functioning of People with Lipoedema According to All Domains of the International Classification of Functioning, Disability and Health: A Scoping Review

“…In total, twenty-seven cross-sectional studies [15,16,, ten cohorts [61][62][63][64][65][66][67][68][69][70], three randomized controlled trials [71][72][73], four controlled clinical trials [74][75][76][77], one clinical trial [78], five case report studies [6,[79][80][81][82], and one qualitative study [83] were included. Two studies used a cross-sectional and a cohort design to answer the research questions [84,85]. Two non-peer-reviewed studies were included in this review.…”