Are factors that influence oocyte fertilization also predictive? An assessment of 148 cycles of in vitro fertilization without gonadotropin stimulation

Ramsewak, Samuel; Cooke, I. D.; Li, Tin‐Chiu; Kumar, Anju; Monks, Nicola J.; Lenton, Elizabeth A.

doi:10.1016/0020-7292(91)90304-n

Cited by 8 publications

(2 citation statements)

References 21 publications

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“…Two-thirds of late spontaneous abortions were multiple pregnancies. In order to avoid a high frequency of multiple pregnancy, natural cycles with single-embryo transfers can be used (21). Alternatively, after ovarian hyperstimulation a maximum of 3 embryos should be transferred and excess embryos could be frozen and thawed for later transfer of only 1 t o 3 eggs per subsequent cycle.…”

Section: -R1mentioning

confidence: 99%

Pregnancy Complications and Short‐Term Follow‐Up of Infants Born After in Vitro Fertilization and Embryo Transfer (IVF/ET)

Wennerholm¹,

Janson²,

Wennergren³

et al. 1991

Acta Obstet Gynecol Scand

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Two hundred and six pregnancies occurring after in vitro fertilization (IVF) and embryo transfer (ET) during a 7-year period in Göteborg were analysed with respect to pregnancy outcome. The clinical abortion rate was 26%, the rate of ectopic pregnancy was 10%, the rate of ongoing pregnancies beyond 24 weeks was 15%, and the rate of deliveries was 49% (n = 100). The hospital records of 98 women with the 100 deliveries resulting in 131 infants were studied. Multiple pregnancy occurred in 27%, including one quadruplet and two triplet pregnancies. Preterm birth occurred in 30% of all pregnancies and in 20% of singleton pregnancies. Thirty-four percent of the infants had a birth weight of less than 2500 g. The perinatal mortality was 46/1000, as estimated from the 24th week of pregnancy. The incidence of major malformation, 2.3%, was similar to that reported from studies in the general population. The first 100 infants born were followed up for 18 months to 8 years. Long-term sequelae were associated with immaturity and low birth weight. No problems during follow-up were disclosed in children who had had an uneventful neonatal period. It is concluded that IVF pregnancies are an obstetric risk group requiring special attention.

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Section: -R1mentioning

confidence: 99%

Pregnancy Complications and Short‐Term Follow‐Up of Infants Born After in Vitro Fertilization and Embryo Transfer (IVF/ET)

Wennerholm¹,

Janson²,

Wennergren³

et al. 1991

Acta Obstet Gynecol Scand

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“…Unstimulated cycles proved ineffective when IVF was used in the treatment of male factor infertility (8,12,13). That is why only individual cases of unstimulated cycles in the treatment of severe cases of male infertility with ICSI can be found in the literature (14).…”

Section: Introductionmentioning

confidence: 99%