2019
DOI: 10.1002/lary.28040
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Are diuretics useful in the treatment of meniere disease?

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Cited by 9 publications
(4 citation statements)
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“…Diuretics have been in use in the treatment of MD for several decades and are thought to reduce the degree of endolymphatic hydrops by reducing the extracellular volume and consequently inducing a decrease of the endolymphatic pressure and volume, either by increased drainage of endolymph or through a reduction in its production at the stria vascularis. Despite the absence of specific experimental and clinical evidence of diuretics' effectiveness [69,70], some studies support diuretic use, with this helping approximately two-thirds of patients achieve substantial control of vertigo attacks when used in association with dietary (low-salt diet and increase of water intake) and lifestyle modifications [71,72]. The use of diuretics and/or betahistine could be offered as an option for maintenance therapy to reduce symptoms or prevent MD attacks [73].…”
Section: Ménière's Disease (Md)mentioning
confidence: 99%
“…Diuretics have been in use in the treatment of MD for several decades and are thought to reduce the degree of endolymphatic hydrops by reducing the extracellular volume and consequently inducing a decrease of the endolymphatic pressure and volume, either by increased drainage of endolymph or through a reduction in its production at the stria vascularis. Despite the absence of specific experimental and clinical evidence of diuretics' effectiveness [69,70], some studies support diuretic use, with this helping approximately two-thirds of patients achieve substantial control of vertigo attacks when used in association with dietary (low-salt diet and increase of water intake) and lifestyle modifications [71,72]. The use of diuretics and/or betahistine could be offered as an option for maintenance therapy to reduce symptoms or prevent MD attacks [73].…”
Section: Ménière's Disease (Md)mentioning
confidence: 99%
“…Considering the pathological EH, diuretics are still commonly used as a first-line therapy for fluid retention ( 20 ). The effectiveness of diuretic therapy in treating vertigo or hearing loss related to MD is not well established and requires a number of critical high-quality randomized control trials ( 21 ). Further, as for acute attack of MD, the anti-inflammatory and immunosuppressive properties of corticosteroids, along with their ability to regulate inner ear homeostasis, are the basis for their mechanism in the treatment of MD.…”
Section: Discussionmentioning
confidence: 99%
“…Zalecane są do kontrolowania objawów choroby, a ich działanie ma polegać na zmniejszaniu ciśnienia, objętości, a nawet produkcji płynu w błędniku. Do najczęściej stosowanych leków wymienianych w badaniach naukowych należą: hydrochlorotiazyd, acetazolamid i chlortalidon [57,58]. Diuretyki często są stosowane jako pierwsza metoda leczenia z uwagi na brak poważnych działań niepożądanych i wpływ na zmniejszenie częstotliwości zawrotów głowy [59].…”
Section: Diuretykiunclassified