Are cyanosed adults with congenital cardiac malformations depressed?

Abstract

To our knowledge, this is the first evidence suggesting a relatively high incidence of depression in adults with congenital cardiac malformations and persistent cyanosis. Larger, multi-centric studies will be needed to confirm or refute these findings.

Exercise performance and quality of life is more impaired in Eisenmenger syndrome than in complex cyanotic congenital heart disease with pulmonary stenosis

“…The significantly worse self-estimated quality of life in ES patients in some domains outline that ES with all its additional burden on cardiovascular and other organ function has an overwhelming impact on almost all domains of life quality. This is in accordance with Lane et al [33] and Popelova et al [34] who found a significant poorer quality of life in all scales of the SF-36 except in "emotional role" and a high incidence of depression in cyanotic patients.…”

Depression and anxiety in adult congenital heart disease: Predictors and prevalence

“…Although these other studies have compared subgroups of ACHD patients with respect to psychosocial variables, this study utilized a broader classification schema which might not allow for comparison between individual lesions. The absence of functional status as a significant predictor in the final model was unexpected, as other researchers have observed a link between ACHD patient functional and psychosocial well-being and QOL [21,23,26,27].…”

Minor symptoms of depression in patients with congenital heart disease have a larger impact on quality of life than limited exercise capacity

“…[8,12,13] Concerning depression, the used methods to assess psychological status by interviews or questionnaires were partially unspecific or too complex. [14] Different studies measured different dimensions of behavioural and emotional problems which lead to not comparable or even contradicting results. Furthermore, most study cohorts were small [15] or confined to simpler lesions [16].…”