Are Benzodiazepines Still the Medication of Choice for Patients With Panic Disorder With or Without Agoraphobia?

Bruce, Steven E.; Vasile, Russell G.; Goisman, Robert M.; Salzman, Carl; Spencer, M B; Machan, Jason T.; Keller, Martin B.

doi:10.1176/appi.ajp.160.8.1432

Cited by 114 publications

(63 citation statements)

References 17 publications

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“…For example, benzodiazepines are found to be ineffective for the treatment of PTSD. However, consistent with previous findings, 14,25,26 the results of the present study indicate that benzodiazepines are used more frequently than SSRIs in the treatment of most anxiety disorders. The reasons for this discrepancy between guideline-recommended care and the findings of naturalistic studies are unknown.…”

Section: Discussionsupporting

confidence: 92%

Treatment of anxiety disorders by psychiatrists from the American Psychiatric Practice Research Network

Sorsdahl

Blanco

Rae

et al. 2013

Rev. Bras. Psiquiatr.

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Objective: Anxiety disorders are highly prevalent in the United States, and if untreated, result in a number of negative outcomes. This study aimed to investigate psychiatrists' current treatment practices for patients with anxiety disorders in the United States. Methods: Psychiatrist-reported data from the 1997 and 1999 American Psychiatric Institute for Research and Education Practice Research Network (PRN) Study of Psychiatric Patients and Treatments (SPPT) were examined, focusing on patients diagnosed with anxiety disorders. Information related to diagnostic and clinical features and treatments provided were obtained. Results: Anxiety disorders remain underdiagnosed and undertreated, since only 11.4% of the sample received a principal diagnosis of an anxiety disorder in a real world setting. Posttraumatic stress disorder was associated with particularly high comorbidity and disability, and social anxiety disorder was relatively rarely diagnosed and treated. Although combined pharmacotherapy and psychotherapy was commonly used to treat anxiety disorders, anxiolytics were more commonly prescribed than selective serotonin reuptake inhibitors (SSRIs). Conclusions: These data provide a picture of diagnosis and practice patterns across a range of psychiatric settings and suggest that anxiety disorders, despite being among the most prevalent of psychiatric disorders remain underdiagnosed and undertreated particularly in respect of the use of psychotherapeutic interventions.

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Section: Discussionsupporting

confidence: 92%

Treatment of anxiety disorders by psychiatrists from the American Psychiatric Practice Research Network

Sorsdahl

Blanco

Rae

et al. 2013

Rev. Bras. Psiquiatr.

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show abstract

“…17 In the United States, over half of the benzodiazepines for anxiety disorders (55%) are prescribed by primary care physicians, followed by psychiatrists and physicians in other specialties (18% and 27%, respectively). 18 In addition, recently published data 19 show that over the past decade benzodiazepines remained the most prescribed medication for panic disorder.…”

Section: Benzodiazepinesmentioning

confidence: 99%

The Role of High-Potency Benzodiazepines in the Treatment of Panic Disorder

Susman¹,

Klee²

2005

Prim. Care Companion CNS Disord.

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“…The efficacy and safety profile of the SSRI paroxetine has been demonstrated in the treatment of panic disorder in a number of randomized controlled trials (17)(18)(19). However, the benzodiazepines remain one of the most commonly prescribed therapeutic options for panic disorder (20).…”

Section: Introductionmentioning

confidence: 99%

Psychopharmacotherapy of panic disorder: 8-week randomized trial with clonazepam and paroxetine

Nardi¹,

Valença²,

Freire³

et al. 2011

Braz J Med Biol Res

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Are Benzodiazepines Still the Medication of Choice for Patients With Panic Disorder With or Without Agoraphobia?

Abstract: These results highlight a gap between pharmacological treatment guidelines and actual delivery of care in that recommendations to use SSRIs to treat panic disorder are not being followed. Factors potentially associated with promoting and ignoring treatment recommendations are discussed.

Cited by 114 publications

References 17 publications

Treatment of anxiety disorders by psychiatrists from the American Psychiatric Practice Research Network

Treatment of anxiety disorders by psychiatrists from the American Psychiatric Practice Research Network

The Role of High-Potency Benzodiazepines in the Treatment of Panic Disorder

Psychopharmacotherapy of panic disorder: 8-week randomized trial with clonazepam and paroxetine

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