Arctium lappa, burdock

Tobyn, Graeme

doi:10.1016/b978-0-443-10344-5.00015-x

Cited by 2 publications

(2 citation statements)

References 36 publications

(24 reference statements)

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“…Flavonoids not only play important roles in mediating the response of plants to biological and non-biological environmental stressors as secondary metabolites [ 37 ], but also are important ingredients in plants with antioxidant, antibacterial, and hypoglycemic activities [ 38 , 39 ]. It has been reported that the tissues of A. lappa contain quercetin, luteolin, quercetin (quercetin and glycoside), flavanol, and other flavonoids [ 7 , 40 ]. However, there was no report related to detect flavonoids in A. lappa using MALDI-TOF MS imaging technology.…”

Section: Resultsmentioning

confidence: 99%

“…A. lappa root exhibits excellent antibacterial and antifungal [ 2 ], antioxidant [ 3 ], anti-inflammatory [ 4 ], and anti-atherosclerosis [ 5 ] properties. These functional properties are attributed to various nutritional components, including polysaccharides, phenolic acids, flavonoids, vitamins, lignans, and polyacetylenes [ 6 , 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

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Visualizing the Spatial Distribution of Arctium lappa L. Root Components by MALDI-TOF Mass Spectrometry Imaging

Qiu

Jiang

et al. 2022

Foods

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This study is aimed at developing novel analytical methods to accurately visualize the spatial distribution of various endogenous components in Arctium lappa L. (A. lappa) roots, and to precisely guide the setting of pre-treatment operations during processing technologies and understand plant metabolism process. The matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) imaging technology was used for visual demonstration of the in situ spatial distribution in A. lappa roots. This work consisted of four steps: matrix selection, section preparation, matrix coating, and MALDI-TOF MS imaging analysis. Consequently, eight saccharides, four caffeoylquinic acids, four flavonoids, six amino acids, one choline, and one phospholipid were imaged and four unidentified components were found. Saccharides were distributed in the center, whereas caffeoylquinic acids and flavonoids were mainly present in the epidermis and cortex. Furthermore, amino acids were mainly detected in the phloem, and choline in the cambium, while phosphatidylserine was found in the secondary phloem and cambium. This study demonstrated that MALDI-TOF MS imaging technology could provide a technical support to understand the spatial distribution of components in A. lappa roots, which would promote the processing technologies for A. lappa roots and help us to understand the plant metabolism process.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Visualizing the Spatial Distribution of Arctium lappa L. Root Components by MALDI-TOF Mass Spectrometry Imaging

Qiu

Jiang

et al. 2022

Foods

View full text Add to dashboard Cite

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Arctigenin-Enriched Burdock Seed Oil (ABSO): A New Skin Brightening Botanical Extract

et al. 2023

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The Arctium lappa L. plant, commonly known as burdock, has been used therapeutically for hundreds of years. Arctigenin (ATG) is an active ingredient in burdock, albeit at low quantities or mostly in the form of acrtiin (arctigenin-4-glucoside). ATG has been touted for its anti-inflammatory properties in many cell types and disease states; however, its role in skin and melanin production has not been extensively studied. Our aims for this study were to develop a burdock seed extract enriched for ATG that is amenable to quasi-drug development, determine in vitro brightening activity, and evaluate safety and skin brightening efficacy clinically in human subjects. Arctiin and ATG content were measured by high-performance liquid chromatography (HPLC). In vitro studies utilized EpiDermTM tissues for skin irritation test, and MelanoDermTM tissues for melanin reduction capacity. A 45 subject clinical study was performed in adult subjects ranging in age from 30 to 60 years old (mean = 41.9 ± 6.7) to test the safety and skin brightening potential of 1% ABSO lotion. We demonstrate by HPLC that ABSO is a natural extract that contains ~5-times more arctigenin than BSO. Furthermore, ABSO inhibits melanin production better than BSO and retains the same melanin-reducing capacity as synthetic ATG in vitro in MelanoDerm™ 3D skin cultures. ABSO also adheres to quasi-drug criteria according to the Japanese Standards of Quasi-Drug Ingredients as determined by infrared absorption spectrum method, unsaponifiable matter, heavy metal and arsenic content, and acid, saponification, and iodine value methods. Clinical assessment of 1% ABSO lotion shows it is well-tolerated in human skin and demonstrates improved brightness and skin tone evenness. ABSO is a natural arctigenin-enriched burdock seed extract that reduces melanin content in vitro and clinically improves skin brightness.

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Arctium lappa, burdock

Cited by 2 publications

References 36 publications

Visualizing the Spatial Distribution of Arctium lappa L. Root Components by MALDI-TOF Mass Spectrometry Imaging

Visualizing the Spatial Distribution of Arctium lappa L. Root Components by MALDI-TOF Mass Spectrometry Imaging

Arctigenin-Enriched Burdock Seed Oil (ABSO): A New Skin Brightening Botanical Extract

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