Archaeosomes for Oral Drug Delivery: From Continuous Microfluidics Production to Powdered Formulations
Ivan Vidakovic,
Karin Kornmueller,
Daniela Fiedler
et al.
Abstract:Archaeosomes were manufactured from natural archaeal lipids by a microfluidics-assisted single-step production method utilizing a mixture of di- and tetraether lipids extracted from Sulfolobus acidocaldarius. The primary aim of this study was to investigate the exceptional stability of archaeosomes as potential carriers for oral drug delivery, with a focus on powdered formulations. The archaeosomes were negatively charged with a size of approximately 100 nm and a low polydispersity index. To assess their suita… Show more
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