The current review describes the recent progress in the
chemistry
and biology of the benzhydryl amines where the central carbon atom
is directly attached to the nitrogen atom of one ring and which have
published in the last five years (2015–2019). Both metal and
metal-free racemic and asymmetric synthetic approaches along with
their activities as anti-leishmanial, antiviral, antibacterial, and
anti-aromatase and other miscellaneous properties are discussed.