Aqueous shunt versus trabeculectomy for treatment of glaucoma

Ordenes-Cavieres, Gonzalo; Pimentel, Eduardo; Schmidt, Jimena

doi:10.5867/medwave.2018.08.7389

Cited by 2 publications

(4 citation statements)

References 15 publications

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“…Concurrently, DKK-1 further promotes tumor growth via non-canonical Wnt/JNK signaling [128]. Pontillo et al reported that Wnt5a (a member of the Wnt family) promotes metastatic PCa cell dormancy via the non-canonical Wnt5a/ROR2/SIAH2 cascade [129]. Rabbani et al extended the characterization of Wnt signaling to PCa metastasis, in which Wnt promotes PCa cells to undergo the EMT via an LRP5-mediated canonical pathway [130].…”

Section: Wnt/β-cateninmentioning

confidence: 99%

Ras and Wnt Interaction Contribute in Prostate Cancer Bone Metastasis

2020

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Prostate cancer (PCa) is one of the most prevalent and malignant cancer types in men, which causes more than three-hundred thousand cancer death each year. At late stage of PCa progression, bone marrow is the most often metastatic site that constitutes almost 70% of metastatic cases of the PCa population. However, the characteristic for the osteo-philic property of PCa is still puzzling. Recent studies reported that the Wnt and Ras signaling pathways are pivotal in bone metastasis and that take parts in different cytological changes, but their crosstalk is not well studied. In this review, we focused on interactions between the Wnt and Ras signaling pathways during each stage of bone metastasis and present the fate of those interactions. This review contributes insights that can guide other researchers by unveiling more details with regard to bone metastasis and might also help in finding potential therapeutic regimens for preventing PCa bone metastasis.

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Section: Wnt/β-cateninmentioning

confidence: 99%

Ras and Wnt Interaction Contribute in Prostate Cancer Bone Metastasis

2020

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Section: Trab Versus Tube Surgerymentioning

confidence: 99%

“…Implants have revolutionized glaucoma surgery, especially in refractory cases [58][59][60][61][62][63][64][65]. A recent metanalysis comparing five systematic reviews on TRAB versus shunt surgeries concluded that shunt surgeries might achieve greater qualified success than TRAB [58]. It is, however, not clear whether the aqueous shunts are superior to TRAB owing to the lack of sufficient evidence with regards to aspects like cost-effectiveness and long-term visual function preservation.…”

Section: Trab Versus Tube Surgerymentioning

confidence: 99%

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Trabeculectomy: Does It Have a Future?

Rao¹,

Cruz²

2022

Cureus

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The trabeculectomy (TRAB) procedure has undergone various modifications to increase the long-term surgical success and safety profiles. The main issues with TRAB include short and long-term complications, that are more common with the concomitant use of anti-fibrotic agents. While many surgeons have predicted the demise of trabeculectomy amidst newer non-penetrating glaucoma surgeries, it is still the gold standard procedure for patients with an advanced or rapidly progressing disease and for those patients who need very low intraocular pressures. This review article is unique in summarizing the evolution of trabeculectomy and its efficacy compared to neoteric shunt procedures while trying to predict if trabeculectomy has a future in the modern surgical world. We have compared the outcomes and complications of trabeculectomy to all the surgical procedures available to date and have tried to evolve an algorithm to help surgeons to decide on their preferred technique.

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Aqueous shunt versus trabeculectomy for treatment of glaucoma

Cited by 2 publications

References 15 publications

Ras and Wnt Interaction Contribute in Prostate Cancer Bone Metastasis

Ras and Wnt Interaction Contribute in Prostate Cancer Bone Metastasis

Trabeculectomy: Does It Have a Future?

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