Aqueous photocatalytic oxidation of amoxicillin

Klauson, Deniss; Babkina, J.; Степанова, К. В.; Krichevskaya, Marina; Preis, Sergei

doi:10.1016/j.cattod.2010.01.015

Cited by 120 publications

(55 citation statements)

References 31 publications

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“…After an accumulation of 10 kJUV L −1 (tir=204 min), this percentage was slowly lowered down to 27 %, showing that the AMX intermediary by-products remaining in solution were more difficult to mineralize. Our results agree with Klauson et al (2010), who reported a 80 % conversion of 20 mg L −1 AMX (initial pH 6.0) using 1 g L −1 of TiO2 after 2 h of exposure to solar radiation in an evaporation dish batch reactor.…”

Section: Resultssupporting

confidence: 92%

“…No losses of nitrogen have been observed from the monitoring of total nitrogen; therefore, the enduring nitrogen atoms are not present in nitrogenated organics adsorbed onto the surface of the catalyst. Lower levels of mineralization of sulfur and nitrogen contained in AMX have been reported by Klauson et al (2010), releasing 14 and 1.4 %, respectively. Elmolla and Chaudhuri (2010b) reported the need of long irradiation times for the mineralization of sulfur contained in a mixture of amoxicillin and two other β-lactam antibiotics in aqueous solution under UV-A/TiO2/H2O2 photocatalysis.…”

Section: Evaluation Of the Amx Mineralizationmentioning

confidence: 76%

“…After pH adjustment to a value around 7.5 with 14 M NaOH (few drops), a sample was taken. This pH value was chosen given that several authors have already reported the influence of pH on TiO2-mediated photocatalytic degradation of AMX and found minimal influence in the near-neutral pH range (Elmolla and Chaudhuri 2010b;Klauson et al 2010;Dimitrakopoulou et al 2012). The suspended catalyst load for photocatalysis was 0.5 g L −1 of TiO2, which is able to absorb all solar UV photons considering an internal photoreactor tube diameter of 46.4 mm (Colina-Márquez et al 2010).…”

Section: Solar Pilot Plantmentioning

confidence: 99%

“…For the enterobacterial strain tested, AMX antibacterial activity with an accumulation of 4.6 kJUVL −1 (tir=110 min) in the system was found to be considerably reduced when growth was compared to the control ( strain studied by the same authors showed to be affected, especially by AMX intermediary byproducts. According to the reaction pathways pro-posed by Klauson et al (2010), some of the AMX photocatalytic by-products (identified via UPLC-ESI-MS analysis) still contain an intact β-lactamic ring structure, which accounts for this residual antibacterial activity. Consequently, in this work, an accumulated UVenergy value of 7.7 kJUVL −1 (tir=180 min) is suggested to be enough to achieve the complete cleavage of the β-lactamic ring, as the solution no longer presented antibacterial activity against S. aureus (Fig.…”

Section: Evaluation Of the Amx Mineralizationmentioning

confidence: 99%

“…Their operation for full chemical degradation can be rather costly, so research is being focused on the application of AOPs that rely on solar irradiation as the source of UV radiation (such as heterogeneous photocatalysis and photo-Fenton reaction) and the possible combination with a pre or post biological treatment step Oller et al 2011). Although several bench-scale studies on different AOPs using simulated UV radiation applied to aqueous solutions of amoxicillin have been undertaken (Elmolla and Chaudhuri 2009;Rizzo et al 2009;Chaudhuri 2010a, b, c, 2011;Dimitrakopoulou et al 2012), only three report results from solar photo-Fenton (Trovó et al 2008;Mavronikola et al 2009) and solar TiO2 (Klauson et al 2010) processes. However, to the best of our knowledge, none so far have neither applied compound parabolic collectors (CPC) as photoreactors, nor have studied the influence of the individual presence of common occurring inorganic ions on the degradation of amoxicillin in aqueous solution.…”

Section: Introductionmentioning

confidence: 99%

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Assessment of solar driven TiO2-assisted photocatalysis efficiency on amoxicillin degradation

Pereira

Reis

Nunes

et al. 2013

Environ Sci Pollut Res

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The objective of this work was to evaluate the efficiency of a solar TiO2-assisted photocatalytic process on amoxicillin (AMX) degradation, an antibiotic widely used in human and veterinary medicine. Firstly, solar photolysis of AMX was compared with solar photocatalysis in a compound parabolic collectors pilot scale photoreactor to assess the amount of accumulated UV energy in the system (QUV) necessary to remove 20 mg L −1 AMX from aqueous solution and mineralize the intermediary byproducts. Another experiment was also carried out to accurately follow the antibacterial activity against Escherichia coli DSM 1103 and Staphylococcus aureus DSM 1104 and mineralization of AMX by tracing the contents of dissolved organic carbon (DOC), low molecular weight carboxylate anions, and inorganic anions. Finally, the influence of individual inorganic ions on AMX photocatalytic degradation efficiency and the involvement of some reactive oxygen species were also assessed. Photolysis was shown to be completely ineffective, while only 3.1 kJUVL −1 was sufficient to fully degrade 20 mg L −1 AMX and remove 61 % of initial DOC content in the presence of the photocatalyst and sunlight. In the experiment with an initial AMX concentration of 2 40 mg L −1 , antibacterial activity of the solution was considerably reduced after elimination of AMX to levels below the respective detection limit. After 11.7 kJUVL −1 , DOC decreased by 71 %; 30 % of the AMX nitrogen was converted into ammonium and all sulfur compounds were converted into sulfate. A large percentage of the remaining DOC was in the form of low molecular weight carboxylic acids. Presence of phosphate ions promoted the removal of AMX from solution, while no sizeable effects on the kinetics were found for other inorganic ions. Although the AMX degradation was mainly attributed to hydroxyl radicals, singlet oxygen also plays an important role in AMX self-photosensitization under UV/ visible solar light.

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Section: Resultssupporting

confidence: 92%

Section: Evaluation Of the Amx Mineralizationmentioning

confidence: 76%

Section: Solar Pilot Plantmentioning

confidence: 99%

Section: Evaluation Of the Amx Mineralizationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Assessment of solar driven TiO2-assisted photocatalysis efficiency on amoxicillin degradation

Pereira

Reis

Nunes

et al. 2013

Environ Sci Pollut Res

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Study of the Electroreactivity of Amoxicillin on Carbon Nanotube‐Supported Metal Electrodes

et al. 2018

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The electroreactivity of amoxicillin (AMX) was studied on catalysts based on platinum, palladium and ruthenium supported on carbon nanotubes (Pt/CNT, Pd/CNT, Ru/CNT) in aqueous media using cyclic voltammetry. Cyclic voltammograms show two oxidation processes, the first one between 0.5 and 1.0 V vs. reference hydrogen electrode (RHE) and the second one between 1.2 and 1.6 V vs. RHE. The effects of electrocatalytic material and supporting electrolyte, on current intensities and oxidation potentials, were determined using experimental design strategy (DOE). Kinetic parameters of the oxidation reactions were calculated from the scan rate study. The constant potential electrolysis of AMX was carried out on Ru/CNT catalyst, in 0.1 M NaOH and AMX conversion reached 45 % after 6 h of electrolysis at 2.5 V vs. RHE. The percentages of CO 3 2À , SO 4 2À and NO 3 À among oxidation products were 26, 17and 4 %, respectively. The primary degradation products of AMX determined by HPLC-MS gave some insight about the reaction pathways.[a] M.

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Photoelectrochemical enzymatic penicillin biosensor: A proof‐of‐concept experiment

Welden

Komesu

Wagner

et al. 2021

Electrochemical Science Adv

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Photoelectrochemical (PEC) biosensors are a rather novel type of biosensors that utilize light to provide information about the composition of an analyte, enabling light-controlled multi-analyte measurements. For enzymatic PEC biosensors, amperometric detection principles are already known in the literature. In contrast, there is only a little information on H + -ion sensitive PEC biosensors. In this work, we demonstrate the detection of H + ions emerged by H + -generating enzymes, exemplarily demonstrated with penicillinase as a model enzyme on a titanium dioxide photoanode. First, we describe the pH sensitivity of the sensor and study possible photoelectrocatalytic reactions with penicillin. Second, we show the enzymatic PEC detection of penicillin.

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Aqueous photocatalytic oxidation of amoxicillin

Cited by 120 publications

References 31 publications

Assessment of solar driven TiO2-assisted photocatalysis efficiency on amoxicillin degradation

Assessment of solar driven TiO2-assisted photocatalysis efficiency on amoxicillin degradation

Study of the Electroreactivity of Amoxicillin on Carbon Nanotube‐Supported Metal Electrodes

Photoelectrochemical enzymatic penicillin biosensor: A proof‐of‐concept experiment

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