2014
DOI: 10.5155/eurjchem.5.3.541-544.1049 View full text |Buy / Rent full text
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Abstract: KEYWORDSHighly substituted pyrimidine/pyrrolidine derivatives were synthesized for the first time in water under neutral conditions by the reaction of aromatic amines, dimethyl/diethyl acetylene dicarboxylates, formaldehyde mediated by β-cyclodextrin (β-CD) in good to excellent yields. β-Cyclodextrin can be recovered and reused without any loss of catalytic activity. The β-Cyclodextrins employed were inexpensive and readily available when compared to other types of cyclodextrins (α, γ).Amines Formaldehyde β-Cy… Show more

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