Aqueous extract of Salvia miltiorrhiza Bunge reduces blood pressure through inhibiting oxidative stress, inflammation and fibrosis of adventitia in primary hypertension

Abstract

Graphical AbstractSABP, an optimized compatibility of four hydrophilic metabolites (DSS, Sal-A, Sal-B and PAL) from Salvia miltiorrhiza Bunge, can reduce the systolic blood pressure in SHR through its antioxidant, anti-inflammatory, anti-vascular remodeling and anti-fibrosis effects.