Aqueous Conversion of Fructose Phosphate Precursor Nanoparticles into Emissive C‐Dot Composite Nanoparticles

Abstract

A one‐pot, fully water‐based synthesis of blue‐ and red‐emitting C‐dots is presented. To this concern, [ZrO]2+[F6P]2− and [Eu(OH)]2+[F6P]2− precursor nanoparticles (F6P: D‐fructose‐6‐phosphate) are prepared in water and converted to C‐dot@[ZrO]2+[HPO4]2− and C‐dot@[Eu(OH)]2+[HPO4]2− composite nanoparticles in boiling water (100 °C) via microwave heating. Composition, structure, and fluorescence of the composite nanoparticles are validated by different analytical methods (e. g., FT‐IR, EA, TG, DLS, SEM, TEM, EDXS). The resulting aqueous suspensions are characterized by high colloidal stability and intense emission. Specifically, C‐dot@[Eu(OH)]2+[HPO4]2− exhibits Eu3+‐type red emission in water. The one‐pot water‐based synthesis with fructose‐containing precursor nanoparticles and the structure of the phosphate‐stabilized C‐dot composite nanoparticles are reported for the first time.

Evaluation of synergistic hybrid nanoparticles for improved diagnosis and treatment of pancreatic cancer

“…The following NPs that were used, all provided by the group of Prof. Claus Feldmann, Karlsruhe Institute of Technology (KIT). The IOH-NPs were synthesized by Dr. Kristina Sabljo 79 as part of her PhD thesis and the Core-Shell NPs by Dr. David Rudolph as part of his PhD thesis.…”