Aquatic toxicology of alkyl-quinolines

Birkholz, Detlef; Coutts, Ronald T.; Hrudey, Steve E.; Danell, Robert; Lockhart, W.L.

doi:10.1016/0043-1354(90)90066-f

Cited by 18 publications

(13 citation statements)

References 27 publications

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“…Mutatox™ test showed both quinoline and isoquinoline (Iso-Q) to be direct genotoxic (Bleeker et al 1999) and ecotoxic (Neuwoehner et al 2009) agents. Quinoline and several monomethyl derivatives have proven to be mutagenic in Salmonella typhimurium after metabolic activation (Eisentraeger et al 2008;Nagao et al 1977), whilst dimethylquinolines have been found to be moderately toxic in the aquatic environment (Birkholz et al 1990). Despite the possible environmental and health impact, little attention has been given to heterocyclic PAHs, probably due to lower concentrations (1-10 %) comparing to those of the analogue homocyclic PAHs (Bleeker et al 2001).…”

Section: Responsible Editor: Ester Heathmentioning

confidence: 99%

The washout effect during laundry on benzothiazole, benzotriazole, quinoline, and their derivatives in clothing textiles

Luongo

Avagyan

Hongyu

et al. 2015

Environ Sci Pollut Res

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In two previous papers, the authors have shown that benzothiazole, benzotriazole, quinoline, and several of their derivatives are widespread in clothing textile articles. A number of these compounds exhibit allergenic and irritating properties and, due to their octanol-water partition coefficient, are prone to be absorbed by the skin. Moreover, they are slightly soluble in water, which could make washing of clothes a route of emission into the environment. In the present study, the washout effect of benzothiazole, benzotriazole, quinoline, and some of their derivatives has been investigated. Twenty-seven textile samples were analyzed before, as well as after five and ten times of washing. The most abundant analyte was found to be benzothiazole, which was detected in 85 % of the samples with an average concentration of 0.53 μg/g (median 0.44 μg/g), followed by quinoline, detected in 81 % of the samples with an average concentration of 2.42 μg/g (median 0.21 μg/g). The average decrease in concentration for benzothiazoles was 50 % after ten times washing, while it was around 20 % for quinolines. The average emission to household wastewater of benzothiazoles and quinolines during one washing (5 kg of clothes made from polyester materials) was calculated to 0.5 and 0.24 g, respectively. These results strongly indicate that laundering of clothing textiles can be an important source of release of these compounds to household wastewater and in the end to aquatic environments. It also demonstrates a potential source of human exposure to these chemicals since considerable amounts of the compounds remain in the clothes even after ten times of washing.

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Section: Responsible Editor: Ester Heathmentioning

confidence: 99%

The washout effect during laundry on benzothiazole, benzotriazole, quinoline, and their derivatives in clothing textiles

Luongo

Avagyan

Hongyu

et al. 2015

Environ Sci Pollut Res

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Section: Discussionmentioning

confidence: 99%

“…Quinolines and other nitrogen-containing heterocyclics are highly toxic [23] and may produce genotoxic [24] and teratogenic [25] effects. Birkholz et al [23] found that the aquatic toxicity of alkyl quinolines varied up to two orders of magnitude and was influenced by the compound's molecular structure and degree of substitution. The 48-h LC50s for Daphnia magna exposed to quinoline and isoquinoline were 28.5 and 4.1 mg/L, respectively, compared to 24.1 mg/L for naphthalene, indicating that these compounds are comparable if not more toxic than their PAH analogs [26].…”

Section: Discussionmentioning

confidence: 99%

Toxicity of water‐soluble fractions derived from whole creosote and creosote‐contaminated sediments

Padma

Hale

Roberts

1998

Enviro Toxic and Chemistry

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Abstract-Creosote, a complex mixture of aromatic compounds (ACs), contaminates numerous sites in the USA and elsewhere. In addition to pollution of the water column directly after a creosote spill, contaminated sediments can continue to act as source of pollution for many years, because natural and anthropogenic perturbations may redissolve or resuspend sediment-associated contaminants. A 48-h static renewal assay compared survival of the bay mysid, Mysidopsis bahia, exposed to water-soluble fractions (WSFs) generated from two different sources: whole creosote and creosote-contaminated sediment. Sediment was obtained from a Super Fund site located on the Southern Branch of the Elizabeth River in Virginia, USA. Whole creosote, contaminated sediment, and WSFs derived from these source materials were characterized. Median lethal concentrations of WSFs generated from whole creosote and sediment (expressed as total identified ACs) were 180 g/L and 700 g/L, respectively. The creosote-derived WSF consisted of more than 70% low molecular weight nitrogen heterocyclics. These heterocyclics were below detectable limits in the sediment-generated WSF, suggesting that losses of these compounds had occurred via weathering. Nitrogen heterocyclics likely contributed to the acute toxicity of the whole creosote WSF.

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“…Creosote is a complex mixture consisting of approximately 3% heterocyclic compounds, 12% phenolic compounds, and 85% polycyclic aromatic hydrocarbons (PAHs) [2]. Many of the nitrogen‐heterocyclic compounds are toxic [3–5], terato‐genic [4], mutagenic [6,7], and/or carcinogenic [8].…”

Section: Introductionmentioning

confidence: 99%

Effects of cations, temperature, and creosote on degradation of indole by Desulfobacterium indolicum (DSM 3383)

Licht

Arvin

Ahring

1997

Enviro Toxic and Chemistry

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This work describes the activity of Desulfobacterium indolicum under different conditions. Hydroxylation of indole by the sulfate‐reducing marine bacterium D. indolicum was related to the concentration of Na+ and Mg2+, whereas K+ and Ca2+ had no influence. Hydroxylation of indole by D. indolicum was possible in normal medium with cation concentrations corresponding to seawater at low temperatures (10‐26°C). The effect of reduced cation concentrations was most pronounced at high temperatures (29 and 36°C) where only an incomplete hydroxylation was observed in the medium with reduced cation concentrations. Desul‐fobacterium indolicum was more sensitive to the presence of an artificial creosote mixture when depleted for cations. Sixty milligrams of artificial creosote per liter inhibited hydroxylation of indole by 30% in a normal growth medium compared to an 86% inhibition in a medium with low concentrations of cations. Indole and quinoline were the only compounds degraded from a creosote mixture consisting of 25 compounds. It was concluded that D. indolicum is active towards indole and quinoline under growth conditions quite distinct from its optimal laboratory conditions.

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Aquatic toxicology of alkyl-quinolines

Cited by 18 publications

References 27 publications

The washout effect during laundry on benzothiazole, benzotriazole, quinoline, and their derivatives in clothing textiles

The washout effect during laundry on benzothiazole, benzotriazole, quinoline, and their derivatives in clothing textiles

Toxicity of water‐soluble fractions derived from whole creosote and creosote‐contaminated sediments

Effects of cations, temperature, and creosote on degradation of indole by Desulfobacterium indolicum (DSM 3383)

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