Aquaporins: Gatekeepers of Fluid Dynamics in Traumatic Brain Injury
Wojciech Czyżewski,
Jakub Litak,
Jan Sobstyl
et al.
Abstract:Aquaporins (AQPs), particularly AQP4, play a crucial role in regulating fluid dynamics in the brain, impacting the development and resolution of edema following traumatic brain injury (TBI). This review examines the alterations in AQP expression and localization post-injury, exploring their effects on brain edema and overall injury outcomes. We discuss the underlying molecular mechanisms regulating AQP expression, highlighting potential therapeutic strategies to modulate AQP function. These insights provide a … Show more
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