Aquagenic Urticaria: A Review of Literature and Case Reports
Abstract:Background: Hypersensitivity to specific stimulus presenting as pruritic wheals is pathognomonic of urticaria, a common malady worldwide, but such vulnerability to water is a rare and a distressing phenomenon requiring considerable lifestyle modifications. Aquagenic urticaria, a rare subtype of urticaria is most probably an allergic response to water. Though histamine is the most potent mediator of the phenomenon, a few reports implied that acetylcholine and genetic predisposition also plays a crucial role in … Show more
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