Aptamers for the Delivery of Plant-Based Compounds: A Review
Joana Gamboa,
Pedro Lourenço,
Carla Cruz
et al.
Abstract:Natural compounds have a high potential for the treatment of various conditions, including infections, inflammatory diseases, and cancer. However, they usually present poor pharmacokinetics, low specificity, and even toxicity, which limits their use. Therefore, targeted drug delivery systems, typically composed of a carrier and a targeting ligand, can enhance natural product selectivity and effectiveness. Notably, aptamers—short RNA or single-stranded DNA molecules—have gained attention as promising ligands in… Show more
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