Aptamers for Personalized Therapeutics

Irfan, Muhammad; Khan, Rizwan Ullah; Qu, Feng

doi:10.1007/978-981-33-4838-7_7

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Nanocarriers Features In Drug Delivery and Cancer Therapy1

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2022

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“…Also, aptamers, have the unique potential in active targeting and diagnostic field. 128 , 130 , 131 Aptamers are single-stranded synthetic sequences of RNA or DNA that fold into secondary and tertiary structures and bind to specific targets (antigens) with extremely high specificity and affinity. Xie et al investigated active targeting MSNs by the use of EpCAM aptamer.…”

Section: Nanocarriers Features In Drug Delivery and Cancer Therapymentioning

confidence: 99%

How Advancing are Mesoporous Silica Nanoparticles? A Comprehensive Review of the Literature

Porrang¹,

Davaran²,

Rahemi³

et al. 2022

IJN

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The application of mesoporous silica nanoparticles (MSNs) is ubiquitous in various sciences. MSNs possess unique features, including the diversity in manufacturing by different synthesis methods and from different sources, structure controllability, pore design capabilities, pore size tunability, nanoparticle size distribution adjustment, and the ability to create diverse functional groups on their surface. These characteristics have led to various types of MSNs as a unique system for drug delivery. In this review, first, the synthesis of MSNs by different methods via using different sources were studied. Then, the parameters affecting their physicochemical properties and functionalization have been discussed. Finally, the last decade’s novel strategies, including surface functionalization, drug delivery, and cancer treatment, based on the MSNs in drug delivery and cancer therapy have been addressed.

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Section: Nanocarriers Features In Drug Delivery and Cancer Therapymentioning

confidence: 99%