Aptamer tuned nanozyme activity of nickel-metal–organic framework for sensitive electrochemical aptasensing of tetracycline residue

Gao, Feng; Zhao, Yanan; Dai, Xiaohui; Xu, Weiwei; Zhan, Fengping; Liu, Yibin; Wang, Qingxiang

doi:10.1016/j.foodchem.2023.137041

Cited by 12 publications

(2 citation statements)

References 50 publications

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“…Apart from detecting disease biomarkers, biological MRE-incorporating MOFs have also been exploited for the EC detection of environmental/food contaminants [186][187][188]. A portable EC biosensor was developed for tetracycline residue detection by incorporating POX-mimic hexahydroxytriphenylene-coordinated nickel (Ni-HHTP) MOFs onto a screen-printed electrode and employing square-wave voltammetry (Figure 8B).…”

Section: Electrochemical Biosensorsmentioning

confidence: 99%

Recent Progress and Prospect of Metal–Organic Framework-Based Nanozymes in Biomedical Application

Baranwal,

Polash,

Aralappanavar

et al. 2024

Nanomaterials

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A nanozyme is a nanoscale material having enzyme-like properties. It exhibits several superior properties, including low preparation cost, robust catalytic activity, and long-term storage at ambient temperatures. Moreover, high stability enables repetitive use in multiple catalytic reactions. Hence, it is considered a potential replacement for natural enzymes. Enormous research interest in nanozymes in the past two decades has made it imperative to look for better enzyme-mimicking materials for biomedical applications. Given this, research on metal–organic frameworks (MOFs) as a potential nanozyme material has gained momentum. MOFs are advanced hybrid materials made of inorganic metal ions and organic ligands. Their distinct composition, adaptable pore size, structural diversity, and ease in the tunability of physicochemical properties enable MOFs to mimic enzyme-like activities and act as promising nanozyme candidates. This review aims to discuss recent advances in the development of MOF-based nanozymes (MOF-NZs) and highlight their applications in the field of biomedicine. Firstly, different enzyme-mimetic activities exhibited by MOFs are discussed, and insights are given into various strategies to achieve them. Modification and functionalization strategies are deliberated to obtain MOF-NZs with enhanced catalytic activity. Subsequently, applications of MOF-NZs in the biosensing and therapeutics domain are discussed. Finally, the review is concluded by giving insights into the challenges encountered with MOF-NZs and possible directions to overcome them in the future. With this review, we aim to encourage consolidated efforts across enzyme engineering, nanotechnology, materials science, and biomedicine disciplines to inspire exciting innovations in this emerging yet promising field.

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Section: Electrochemical Biosensorsmentioning

confidence: 99%

Recent Progress and Prospect of Metal–Organic Framework-Based Nanozymes in Biomedical Application

Baranwal,

Polash,

Aralappanavar

et al. 2024

Nanomaterials

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“…They then built an electrochemical TC aptamer sensor by regulating the Ni-HHTP nanozyme activity, which was used for detecting TC residues in fresh carp and milk. 34…”

Section: Introductionmentioning

confidence: 99%

Deep eutectic solvent-assisted synthesis of La–Ce hybrid nanorods for the colorimetric determination of tetracycline in foods

An,

Li,

Chen

et al. 2024

Anal. Methods

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Rational Integration of Nanozyme Probe and Smartphone Device for On‐Site Analysis

Wu,

Zhou,

Chen

et al. 2024

Analysis & Sensing

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On‐site detection featuring miniaturized, integrated analytical device and rapid data feedback has encouraged a great deal of attention, especially in the current context of pandemic diseases occurring with high frequency worldwide. This convenient detection device constitutes a stable recognition element and a portable signal treatment and readout module. In this regard, the enzyme‐mimic nanomaterials (nanozymes) with the merits of structural stability, cost efficiency, scale‐up synthesis and high recyclability well meet the requirements for recognition unit set‐up. While the all‐pervading smartphone, which enables the data collection through photography or wireless transmission, holds numerous opportunities in the design of hand‐held analytical device. In this review, we summarize the advances of nanozyme‐smartphone integrated platforms, with special emphasis of the signal transduction principles involving colorimetric, chemiluminescence, and electrochemical signals. The diversified on‐site applications in terms of biological, environment and food analysis are showcased. Finally, the current challenges as well as thefuture perspectives on nanozyme design, sensing diversity and smartphone analysis are discussed.

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Aptamer tuned nanozyme activity of nickel-metal–organic framework for sensitive electrochemical aptasensing of tetracycline residue

Cited by 12 publications

References 50 publications

Recent Progress and Prospect of Metal–Organic Framework-Based Nanozymes in Biomedical Application

Recent Progress and Prospect of Metal–Organic Framework-Based Nanozymes in Biomedical Application

Deep eutectic solvent-assisted synthesis of La–Ce hybrid nanorods for the colorimetric determination of tetracycline in foods

Rational Integration of Nanozyme Probe and Smartphone Device for On‐Site Analysis

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