Aptamer-guided Selective Delivery of Therapeutics to Breast Cancer Cells
Expressing Specific Biomarkers
Swaroop Kumar Pandey,
Mradula Parul,
Manikandan Santhanam
Abstract:Cancer biomarkers or tumor-associated antigens (TAA) are the focus area of current research
in cancer biology for diagnosis, prognosis, screening, and targeted treatments. Breast cancer is
the second most common type of cancer, affecting women more than men. Conventional methods and
antibody-targeted therapies are less effective and suffer systemic cytotoxicity, poor tissue sensitivity,
low penetration capacity, and reduced accumulation of the drug in tumor cells that limit its application
and sometimes result… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.