Appropriateness of antimicrobial prophylaxis practices according to the guidelines in two common gynaecological surgeries

Khan, Junaid Sarfraz; Khan, Asghar; Kamran, Sohail; Jamal, Muhammad Nasir; Sherwani, Sikandar Khan; Khan, Zakir

doi:10.4103/tjog.tjog_85_19

Trop J Obstet Gynaecol

2020

DOI: 10.4103/tjog.tjog_85_19

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Appropriateness of antimicrobial prophylaxis practices according to the guidelines in two common gynaecological surgeries

Junaid Sarfraz Khan

Asghar Khan

Sohail Kamran

et al.

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“…Santos et alstated that of 306 gynecological surgeries, the compliance with the timing of prophylactic antibiotics was 97.4%17 . Khan et al stated that the adherence rate to surgical prophylaxis guidelines for timing was 56.4% of the 264 patients who underwent cesarean and hysterectomy procedures26 . Mehdi et al stated that the inappropriateness in timing regarding SAP use was 30.2%18 .…”

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This review aims to analyze the appropriateness of surgical antimicrobial prophylaxis in obstetrics and gynecology from 2015 to June 2022. Methodology: The review includes interventional, prospective and retrospective observational studies and surveys based on compliance with surgical antibiotic prophylaxis use concerning standard surgical antimicrobial prophylaxis (SAP) guidelines for gynecological and obstetrics surgeries from a web search of PubMed and Google Scholar from the year of 2015 to June 2022. Results: The review describes 33 studies focused on the appropriate usage of surgical prophylactic antibiotics. The majority of the studies revealed excessive and inappropriate use, and the compliance is far below the recommended guidelines, especially in terms of duration which is followed by the selection and time of administration of antibiotics. Conclusion: The majority of the studies analyzed in this review indicated a remarkable rate of inappropriateness, which may contribute to antimicrobial resistance (AMR), which raises the risk of SSI exacerbated by resistant bacteria followed by prolonged hospitalization and increased mortality. There is evidence that pharmacist intervention promotes the optimal use of SAP. Hence Antimicrobial stewardship (AMS) interventions such as periodic audits and educational interventions should be implemented to improve the appropriate use of SAP and to prevent the emergence of AMR. INTRODUCTION:Surgical site infections are one of the most commonly diagnosed infections associated with health care in economically developing low and middle-income countries, leading to longer hospital stays, readmissions, increased mortality and morbidity rates, and also increasing financial burden 1, 2 .

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Appropriateness of antimicrobial prophylaxis practices according to the guidelines in two common gynaecological surgeries

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References 2 publications

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