Appropriate adherence to antiretroviral therapy in the Alto Paranaiba, Minas Gerais, Brazil

Souza, Gabriela de Nardi; Tibúrcio, Aline Andréia Caixeta Magalhães; Koike, Marcia Kiyomi

doi:10.5935/medicalexpress.2016.03.05

Cited by 7 publications

(14 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The flow diagram of study selection is shown in Figure . Fifty‐three studies, composed of 22,603 participants in ART from 25 LAC countries, met eligibility criteria for the systematic review (Table ) . The median number of participants in ART per study was 201 [range: 13 – 3343; interquartile range (IQR): 394 – 125].…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Adherence to antiretroviral therapy for HIV/AIDS in Latin America and the Caribbean: Systematic review and meta‐analysis

et al. 2018

View full text Add to dashboard Cite

IntroductionOptimal adherence to antiretroviral therapy is closely related with suppression of the HIV viral load in plasma, slowing disease progression and decreasing HIV transmission rates. Despite its importance, the estimated proportion of people living with HIV in Latin America and the Caribbean with optimal adherence has not yet been reported in a meta‐analysis. Moreover, little is known of the factors leading to poor adherence which may be setting‐specific. We present a pooled estimate of adherence to antiretroviral therapy (ART) of people living with HIV in Latin America and Caribbean, report the methods used to measure adherence and describe the factors associated with poor adherence among the selected studies.MethodsWe electronically searched published studies up to July 2016 on the PubMed, Web of Science and Virtual Health Library (Latin America and the Caribbean Regional Portal); considering the following databases: MEDLINE, LILACS, PAHO and IBECS. Two independent reviewers selected and extracted data on ART adherence and study characteristics. Pooled estimate of adherence was derived using a random‐effects model. Risk of bias in individual studies was assessed independently by two investigators using the Risk of Bias Assessment tool for Non‐randomized Studies (RoBANS).Results and discussionThe meta‐analysis included 53 studies published between 2005 and 2016, which analysed 22,603 people living with HIV in 25 Latin America and Caribbean countries. Overall adherence in Latin America and Caribbean was 70% (95% CI: 63–76; I 2 = 98%), similar to levels identified by studies conducted in high‐income regions. Self‐report was the most frequently used method to measure adherence. Subgroup analysis showed that adherence was higher for the shortest recall time frame used, as well as in countries with lower income level, Gross National Income (GNI) per capita and Human Development Index (HDI). Studies reported diverse adherence barriers, such as alcohol and substance misuse, depression, unemployment and pill burden.ConclusionsOur study suggests that adherence to ART in Latin America and Caribbean may be below the sufficient levels required for a successful long‐term viral load suppression.

show abstract

Section: Resultsmentioning

confidence: 99%

“…In Souza et al. (2016) , only the self‐reported adherence measure was considered because the adherence as measured from medication dispensing data addressed a period greater than three months (the whole study period).…”

Section: Resultsmentioning

confidence: 99%

Adherence to antiretroviral therapy for HIV/AIDS in Latin America and the Caribbean: Systematic review and meta‐analysis

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Fisher's Exact Test and Pearson's Chi-Square were then used to verify the association of NDs, which had a frequency of over 50% in people living with AIDS, with the following sociodemographic and clinical characteristics: age, gender, marital status, family income, modes of transmission of HIV, existence of other diseases, current opportunistic infection, abandonment of treatment, difficulty in accessing to service, being smoker, alcohol consumer and drug user. The characteristics frequently studied in research involving people living with AIDS (9)(10)(11)(12)(13)(14)(15) were used. There was a significance level of 5%.…”

Section: Analysis Of Results and Statisticsmentioning

confidence: 99%

“…It is known that the use of antiretroviral agents slows down the accelerated growth of virus infectivity, but continuous and uninterrupted use is necessary to improve the quality of life of people living with AIDS and to reduce the incidence of secondary comorbidities such as pneumonia, tuberculosis and candidiasis. In this sense, health policy interventions should aim not only at the distribution of medication, but at the follow-up of these people at home, building networks of support with Primary Health Care (10) .…”

Section: Discussionmentioning

confidence: 99%

People living with AIDS: Association between nursing diagnoses and sociodemographic/clinical characteristics

et al. 2018

View full text Add to dashboard Cite

Objective: To analyze the association between nursing diagnoses and sociodemographic and clinical characteristics in people living with AIDS. Method: Cross-sectional study with 100 people living with AIDS in a University Hospital. Data collection took place between January and July 2015, using an interview script and physical examination. The association occurred through Pearson's Chi-Square Test and Fisher's Exact Test. Results: The most prevalent nursing diagnoses were: ineffective protection, poor knowledge, lack of adherence and sexual dysfunction. Significant associations were observed among nursing diagnoses with the following sociodemographic and clinical characteristics: marital status, place of residence, level of schooling, family income, modes of transmission of acquired immunodeficiency virus, current opportunistic infection, abandonment of treatment, difficulty of access to health services and use of alcohol and illicit drugs. Conclusion: The diagnoses presented significant associations with sociodemographic and clinical aspects.

show abstract

“…Contudo, apesar dos benefícios e da gratuidade do tratamento no país, muitas pessoas ainda não conseguem aderir à terapia, alegando dificuldade na ingestão dos comprimidos e com os efeitos adversos com o tratamento (SOUZA; TIBURCIO; KOIKE, 2016;STERRANTINO et al, 2012).…”

Section: Gir 2016)unclassified

Estigmatização de pessoas que vivem com HIV/aids e sua relação com suporte social e qualidade de vida

Caliari¹

View full text Add to dashboard Cite

Appropriate adherence to antiretroviral therapy in the Alto Paranaiba, Minas Gerais, Brazil

Cited by 7 publications

References 7 publications

Adherence to antiretroviral therapy for HIV/AIDS in Latin America and the Caribbean: Systematic review and meta‐analysis

Adherence to antiretroviral therapy for HIV/AIDS in Latin America and the Caribbean: Systematic review and meta‐analysis

People living with AIDS: Association between nursing diagnoses and sociodemographic/clinical characteristics

Estigmatização de pessoas que vivem com HIV/aids e sua relação com suporte social e qualidade de vida

Contact Info

Product

Resources

About