Approach to the Treatment of Limb Disorders With Botulinum Toxin A

Abstract

Botulinum toxin A was found to be a safe and useful treatment of various limb conditions. Botulinum toxin A was significantly more effective when only a few muscles needing low doses were injected, and tended to be more useful in dystonia and spasticity than tremor. Candidates for BTX injection could be categorized functionally into 3 groups independent of the underlying disorders. The only significant adverse effect of BTX injection in limbs was transient weakness in injected or neighboring muscles.

Botulinum toxin and occupational therapy in the treatment of writer's cramp

“…In this study, we examined the efficacy of BTX injections and a structured occupational therapy program in the treatment of WC. In accordance with most studies [2,3,10,16,17,20,21] we confirm that BTX is presently the most efficacious form of treatment of this disorder. Fifty-eight percent of patients responded to BTX injections with 23% having a marked benefit and 35% a moderate response.…”

Botulinum toxin and occupational therapy in the treatment of writer's cramp

“…In this study, we examined the efficacy of BTX injections and a structured occupational therapy program in the treatment of WC. In accordance with most studies [2,3,10,16,17,20,21] we confirm that BTX is presently the most efficacious form of treatment of this disorder. Fifty-eight percent of patients responded to BTX injections with 23% having a marked benefit and 35% a moderate response.…”

Effective Management of Upper Limb Parkinsonian Tremor by IncobotulinumtoxinA Injections Using Sensor-based Biomechanical Patterns

“…Visually-based versus kinematically-based treatments were not compared as prior studies have already shown the lack of reproducibility and tolerability using visually guided, fixed schedule injections. 11 – 15 , 17 , 18 The sample size is similar to other reported studies in the literature. 2 , 11 – 15 , 18 , 21 , 24 , 25 , 27 …”

Effective Management of Upper Limb Parkinsonian Tremor by IncobotulinumtoxinA Injections Using Sensor-based Biomechanical Patterns

“…Visually-based versus kinematically-based treatments were not compared as prior studies have already shown the lack of reproducibility and tolerability using visually guided, fixed schedule injections. [11][12][13][14][15]17,18 The sample size is similar to other reported studies in the literature. 2,11-15, 18,21,24,25,27 This study shows that individual, objective measurement of tremor at each joint in the upper limb affected by tremor allows for proper characterization and treatment of PD patients.…”

Botulinum toxin and occupational therapy in the treatment of writer's cramp

“…In this study, we examined the efficacy of BTX injections and a structured occupational therapy program in the treatment of WC. In accordance with most studies [2,3,10,16,17,20,21] we confirm that BTX is presently the most efficacious form of treatment of this disorder. Fifty-eight percent of patients responded to BTX injections with 23% having a marked benefit and 35% a moderate response.…”

Effective Management of Upper Limb Parkinsonian Tremor by IncobotulinumtoxinA Injections Using Sensor-based Biomechanical Patterns

“…Visually-based versus kinematically-based treatments were not compared as prior studies have already shown the lack of reproducibility and tolerability using visually guided, fixed schedule injections. 11 – 15 , 17 , 18 The sample size is similar to other reported studies in the literature. 2 , 11 – 15 , 18 , 21 , 24 , 25 , 27 …”

Effective Management of Upper Limb Parkinsonian Tremor by IncobotulinumtoxinA Injections Using Sensor-based Biomechanical Patterns

“…Visually-based versus kinematically-based treatments were not compared as prior studies have already shown the lack of reproducibility and tolerability using visually guided, fixed schedule injections. [11][12][13][14][15]17,18 The sample size is similar to other reported studies in the literature. 2,11-15, 18,21,24,25,27 This study shows that individual, objective measurement of tremor at each joint in the upper limb affected by tremor allows for proper characterization and treatment of PD patients.…”

Botulinum toxin and occupational therapy in the treatment of writer's cramp

“…In this study, we examined the efficacy of BTX injections and a structured occupational therapy program in the treatment of WC. In accordance with most studies [2,3,10,16,17,20,21] we confirm that BTX is presently the most efficacious form of treatment of this disorder. Fifty-eight percent of patients responded to BTX injections with 23% having a marked benefit and 35% a moderate response.…”

Effective Management of Upper Limb Parkinsonian Tremor by IncobotulinumtoxinA Injections Using Sensor-based Biomechanical Patterns

“…Visually-based versus kinematically-based treatments were not compared as prior studies have already shown the lack of reproducibility and tolerability using visually guided, fixed schedule injections. 11 – 15 , 17 , 18 The sample size is similar to other reported studies in the literature. 2 , 11 – 15 , 18 , 21 , 24 , 25 , 27 …”

Effective Management of Upper Limb Parkinsonian Tremor by IncobotulinumtoxinA Injections Using Sensor-based Biomechanical Patterns

“…Visually-based versus kinematically-based treatments were not compared as prior studies have already shown the lack of reproducibility and tolerability using visually guided, fixed schedule injections. [11][12][13][14][15]17,18 The sample size is similar to other reported studies in the literature. 2,11-15, 18,21,24,25,27 This study shows that individual, objective measurement of tremor at each joint in the upper limb affected by tremor allows for proper characterization and treatment of PD patients.…”